Evidence map›Paper›PMID 38287664›Full record

ArticleAsian spine journal2024

Association between Osteoporosis and Skeletal Muscle Mass in Men.

Masaya Mizutani, Yawara Eguchi, Toru Toyoguchi, Sumihisa Orita, Kazuhide Inage, Yasuhiro Shiga, Satoshi Maki, Junichi Nakamura, Shigeo Hagiwara, Yasuchika Aoki and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Asian spine journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Impact of smoking, diabetes, and exercise on dementia risk in women with osteoporosis: a nationwide cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Masaya MizutaniDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Yawara EguchiDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Toru ToyoguchiDepartment of Orthopaedic Surgery, Chiba Qiball Clinic, Chiba, Japan.
Sumihisa OritaDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Kazuhide InageDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Yasuhiro ShigaDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Satoshi MakiDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Junichi NakamuraDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Shigeo HagiwaraDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Yasuchika AokiDepartment of Orthopaedic Surgery, Eastern Chiba Medical Center, Togane, Japan.
Masahiro InoueDepartment of Orthopaedic Surgery, Eastern Chiba Medical Center, Togane, Japan.
Masao KodaDepartment of Orthopedic Surgery, University of Tsukuba, Tsukuba, Japan.
Hiroshi TakahashiDepartment of Orthopedic Surgery, University of Tsukuba, Tsukuba, Japan.
Tsutomu AkazawaDepartment of Orthopaedic Surgery, St. Marianna University School of Medicine, Kawasaki, Japan.
Seiji OhtoriDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Chiba University · JPTeikyo University Chiba Medical Center · JPUniversity of Tsukuba · JPChiba Hospital · JPSt. Marianna University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designCross-sectional study. PURPOSE: This cross-sectional study aimed to investigate the risk factors for osteoporosis in men by assessing bone mineral density (BMD), skeletal muscle mass, body fat mass, grip strength, and advanced glycation end products (AGEs). OVERVIEW OF LITERATURE: Fewer studies have reported the correlation between BMD and skeletal muscle mass in women. Moreover, a few studies have examined the relationship between osteoporosis and skeletal muscle mass.

methodsThis study included 99 men (mean age, 74.9 years; range, 28-93 years) who visited Qiball Clinic for BMD and body composition examinations. The osteoporosis group consisted of 24 patients (mean age, 72.5 years; range, 44-92 years), and the control group consisted of 75 individuals (mean age, 74.9 years; range, 28-93 years). Whole-body skeletal muscle mass was measured using a bioelectrical impedance analyzer. BMD was measured by dual X-ray absorptiometry. Skin autofluorescence (SAF), a marker of dermal AGE accumulation, was measured using a spectroscope. Osteoporosis was defined as a bone density T score of -2.5 or less. Physical findings, skeletal muscle mass, BMD, grip strength, and SAF were compared between the osteoporosis and control groups.

resultsThe osteoporosis group had significantly lower trunk muscle mass (23.1 kg vs. 24.9 kg), lower leg muscle mass (14.4 kg vs. 13.0 kg), and skeletal mass index (7.1 kg/m2 vs. 6.7 kg/m2) than the control group (all p<0.05). Lower limb muscle mass was identified as a risk factor for osteoporosis in men (odds ratio, 0.64; p=0.03).

conclusionsConservative treatment of osteoporosis in men will require an effective approach that facilitates the maintenance or strengthening of skeletal muscle mass, including exercise therapy with a focus on lower extremities and nutritional supplementation.

Indexed as

MaleOsteoporosisSkeletal muscle mass

Identifiers

PMID38287664
PMCPMC10910132
OpenAlexW4391359726

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.