Evidence map›Paper›PMID 38287253›Full record

Trial reportBMC geriatrics2024

Prevalence of iron deficiency in patients admitted to a geriatric unit: a multicenter cross-sectional study.

Bertrand Fougère, François Puisieux, Pascal Chevalet, Cédric Annweiler, Emeline Michel, Laure Joly, Frédéric Blanc, Abdelghani El Azouzi, Valérie Desré-Follet, Patrice Cacoub and 1 more

Registry-linked trialOpen access · goldAbstract readClinical TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05514951 (Study of the Prevalence of Iron Deficiency in Elderly Patient in Hospital Environment), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05514951 nacompletednot on this map

Study of the Prevalence of Iron Deficiency in Elderly Patient in Hospital Environment

TypeinterventionalSponsorVifor PharmaRan2022 to 2022Enrolled888ConditionsIron-deficiencyArmsBlood sampling
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 1 country.

Bertrand FougèreDivision of Geriatric Medicine, Tours University Hospital, Tours, France. bertrand.fougere@univ-tours.fr.
François PuisieuxLille Université, CHU Lille, Pôle de Gérontologie, Lille, France.
Pascal ChevaletNantes Université, CHU Nantes, Pôle de Gérontologie Clinique, Nantes, France.
Cédric AnnweilerDepartment of Geriatric Medicine and Memory Clinic, Research Center On Autonomy and Longevity, University Hospital & Laboratoire de Psychologie Des Pays de La Loire, LPPL EA 4638, SFR Confluences, University of Angers, Angers, France.
Emeline MichelUniversité Côte d'Azur, Centre Hospitalier Universitaire de Nice, Nice, France.
Laure JolyGeriatric Department, CHRU Nancy, Université de Lorraine, Nancy, France.
Frédéric BlancTeam IMIS, ICube Laboratory, UMR 7357 and FMTS (Fédération de Médecine Translationnelle de Strasbourg), University of Strasbourg and CNRS, Strasbourg, France.
Abdelghani El AzouziGeriatric Department, Dunkirk, CH Dunkirk, France.
Valérie Desré-FolletCSL Vifor, Paris La Défense, France.
Patrice CacoubUMR 7211, and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Sorbonne Universités, UPMC Univ Paris 06, Paris, France.
CARENFER PA study group*
Inserm · FRCentre National de la Recherche Scientifique · FRLaboratoire de Psychologie des Pays de la Loire · FRNantes Université · FRUniversité Côte d'Azur · FRUniversité de Lille · FRUniversité de Tours · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIron deficiency (ID) is often associated with other comorbidities in older patients and is a factor of morbimortality. However, the prevalence of ID remains poorly documented in this population.

methodsThe CARENFER PA study was a French multicenter cross-sectional study whose objective was to evaluate ID in patients (> 75 years) admitted to a geriatric unit. The primary endpoint was the ID prevalence defined as: serum ferritin < 100 µg/L and/or transferrin saturation coefficient (TSAT) < 20%. The Short Physical Performance Battery (SPPB) test was used to identify older patients at high risk of adverse events (e.g., disability, falls, hospitalization, death).

resultsA total of 888 patients (mean age, 85.2 years; women, 63.5%) from 16 French centers were included from October 2022 to December 2022. The prevalence of ID was 57.6% (95% CI, 54.3-60.9) in the cohort of older patients (62.6% in anemic and 53.3% in non-anemic patients; p = 0.0062). ID prevalence increased significantly with the presence of more than three comorbidities (65.6% vs. 55.9%; p = 0.0274), CRP ≥ 12 mg/L (73.0% vs. 49.3%; p < 0.001) and treatment that may influence ID/anemia (60.5% vs. 49.6%; p = 0.0042). In multivariate analysis, only CRP ≥ 12 mg/L was an independent predictive factor of ID (odds ratio, 2.78; 95% CI, 1.92-4.08; p < 0.001). SPPB scores were low (0-6) in 60.5% of patients with ID versus 48.6% of patients without ID (p = 0.0076).

conclusionMore than half of older patients had ID, including non-anemic patients. ID was associated with the presence of inflammation and a low SPPB score.

trial registrationNCT05514951.

Indexed as

Anemia, Iron-DeficiencyIron DeficienciesAgedAged, 80 and overCross-Sectional StudiesFemaleHospitalizationHumansMalePrevalenceAnemiaIntravenous ironIron deficiencyOlder patientSerum ferritinTransferrin saturation

Identifiers

PMID38287253
PMCPMC10826072
OpenAlexW4391328423

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.