Evidence map›Paper›PMID 38287136›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2024

NRBC concentrations over time in neonates with moderate to severe neonatal encephalopathy with and without sentinel events.

Pratima Gaulee, Nikolay Bliznyuk, Dhanashree Rajderkar, Georgia Graham, Livia Sura, Jamie Harris, James L Wynn, Michael D Weiss

Abstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Reference intervals for circulating nucleated red blood cell counts of neonates, improved by the refineR algorithm.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pratima GauleeDepartment of Pediatrics, University of Florida, Gainesville, FL, 32610, USA.
Nikolay BliznyukDepartments of Agricultural and Biological Engineering, Biostatistics and Statistics, University of Florida, Gainesville, FL, 32611, USA.
Dhanashree RajderkarDepartment of Radiology, University of Florida, Gainesville, FL, 32610, USA.ORCID 0000-0002-5962-2854
Georgia GrahamDepartment of Gynecology and Obstetrics, University of Florida, Gainesville, FL, 32610, USA.
Livia SuraDepartment of Pediatrics, University of Florida, Gainesville, FL, 32610, USA.
Jamie HarrisDepartment of Pediatrics, University of Florida, Gainesville, FL, 32610, USA.
James L WynnDepartment of Pediatrics, University of Florida, Gainesville, FL, 32610, USA.ORCID 0000-0001-7052-4836
Michael D WeissDepartment of Pediatrics, University of Florida, Gainesville, FL, 32610, USA. mweiss@ufl.edu.ORCID 0000-0002-4567-9286

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the serum concentrations of nucleated red blood cells (NRBC) over time in neonates with moderate to severe neonatal encephalopathy (NE). STUDY

designA retrospective cohort study with subjects subdivided into three groups: definite sentinel events (n = 52), probable sentinel events (n = 20) and no history of sentinel events (n = 63). Peak absolute NRBC and NRBC/100 WBC were compared between groups and with MRI Injury score, cord and admission pH/base deficit.

resultsAbsolute NRBC peaked at 24.05 h after birth (CI: 15.30-32.79), 17.56 h after birth (CI: 7.35-27.77), and 39.81 h after birth (CI: 28.73-50.89) in each respective group. The peak in absolute NRBC correlated with the severity of injury in the grey matter in group 2 and white matter in groups 1 and 2. Higher peak absolute NRBC value correlated to a lower admission ABG pH.

conclusionNRBC peak at 24 h after birth in neonates with sentinel events.

Indexed as

Magnetic Resonance ImagingBrain DiseasesErythroblastsFemaleHumansHypoxia-Ischemia, BrainInfant, NewbornMaleRetrospective StudiesSeverity of Illness Index

Identifiers

PMID38287136

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.