Evidence map›Paper›PMID 38286939›Full record

ArticleActa neurochirurgica2024

Stability of infundibular dilatations: a single center follow-up study and systematic review of the literature.

Jeremias Tarkiainen, Liisa Pyysalo, Tero Hinkka, Juha-Pekka Pienimäki, Antti Ronkainen, Juhana Frösen

Open access · hybridAbstract read
In one paragraph

Article in Acta neurochirurgica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jeremias TarkiainenDepartment of Neurosurgery, Tampere University Hospital and University of Tampere, Tampere, Finland. jeremias.tarkiainen@tuni.fi.ORCID 0000-0002-5997-2184
Liisa PyysaloHemorrhagic Brain Pathology Research Group, Faculty of Medical Technology and Health Sciences, Tampere University, Tampere, Finland.
Tero HinkkaDepartment of Radiology, Tampere University Hospital and University of Tampere, Tampere, Finland.
Juha-Pekka PienimäkiDepartment of Radiology, Tampere University Hospital and University of Tampere, Tampere, Finland.
Antti RonkainenDepartment of Neurosurgery, Tampere University Hospital and University of Tampere, Tampere, Finland.
Juhana FrösenDepartment of Neurosurgery, Tampere University Hospital and University of Tampere, Tampere, Finland.
Tampere University Hospital · FITampere University · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAlthough infundibular dilatations (IDs) have been thought to be benign anatomical variants, case reports suggest that they can grow and rupture. The aim of this study was to determine whether IDs have a tendency to grow or rupture.

methodsThe study population was collected from the Tampere University Hospital (TAUH) Aneurysm Database. The presence of IDs was screened from the medical records and imaging studies of 356 intracranial aneurysm patients left to follow-up from 2005 to 2020. The imaging studies were reviewed to confirm the IDs, and their clinical course. Finally, we performed a systematic review of published cases of ID leading to aneurysmatic rupture from PubMed.

resultsWe found 97 typical IDs in 83 patients and 9 preaneurysmal lesions resembling ID in 9 patients. Out of the typical cone-shaped IDs, none grew or ruptured in a total follow-up of 409 patient-years. One preaneurysmal lesion ruptured during a follow-up: this lesion had components of both infundibular dilatation and aneurysm at the beginning of follow-up. In the systematic literature search, we found 20 cases of aneurysmatic SAHs originating from an ID. Of those, only 7 had imaging available prerupture. All 7 IDs were typically cone-shaped, but a branching vessel originating from the apex of ID was only seen in 4/7.

conclusionTypical infundibular dilatations seem to be benign anatomical variants that are stable and, thus, do not need prophylactic treatment or imaging follow-up. Likely, the SAHs reported from IDs were actually caused by misdiagnosed preaneurysmal lesions.

Indexed as

Aneurysm, RupturedIntracranial AneurysmCerebral AngiographyDilatationDilatation, PathologicFollow-Up StudiesHumansSystematic Reviews as TopicAneurysmFollow-upInfundibular dilatationSubarachnoid hemorrhage

Identifiers

PMID38286939
PMCPMC10824818
OpenAlexW4391328367

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.