Evidence map›Paper›PMID 38286817›Full record

ArticleArchives of gynecology and obstetrics2024

Risks associated with antidepressants in patients with hypertension during pregnancy: a retrospective cohort study.

Marlieke Oude Weernink, Elvera A Damer, Mireille A Edens, Bas S W A Nij Bijvank, Marieke A C Hemels, Peter G J Ter Horst

Abstract read
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In one paragraph

Article in Archives of gynecology and obstetrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Marlieke Oude WeerninkDepartment of Clinical Pharmacy, Isala Klinieken, dr van Heesweg 2, 8025 AB, Zwolle, The Netherlands.
Elvera A DamerDepartment of Psychiatry, Isala, Zwolle, The Netherlands.
Mireille A EdensIsala Academie, Isala, Zwolle, The Netherlands.
Bas S W A Nij BijvankDepartment of Gynecology and Obstetrics, Isala, Zwolle, The Netherlands.
Marieke A C HemelsDepartment of Neonatology, Isala, Zwolle, The Netherlands.
Peter G J Ter HorstDepartment of Clinical Pharmacy, Isala Klinieken, dr van Heesweg 2, 8025 AB, Zwolle, The Netherlands. p.g.j.ter.horst@isala.nl.ORCID 0000-0003-1914-5907
Isala · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn a cohort of pregnant women using antihypertensive drugs, we compared exposure to antidepressants versus no exposure and the possible association with birth weight, APGAR scores, NICU admission, and maternal admission to an obstetrical intensive care unit (OHC). It was hypothesized that pregnant women with hypertensive disorders using antidepressants are at greater risk of complications.

methodsA retrospective cohort study in a general teaching hospital in Zwolle, in the Middle-Northern part of The Netherlands. Finally, 58 pregnancies in the exposed group and 273 pregnancies in the reference group met all inclusion and exclusion criteria. We compared the neonate's birthweight between the exposed to antidepressants group and the reference group as the primary outcome. Secondary outcomes were the APGAR score at 1 and 5 min and obstetric high care (OHC) admission of the mother and neonatal intensive care unit (NICU) admission of the child.

resultsWe found no differences in birth weight in neonates of mothers with hypertensive disorders and whether or not to use antidepressants. Besides a possible higher risk of admission to an OHC in women with hypertension-complicated pregnancies using antidepressants, we found no other maternal or neonatal risks in this population.

conclusionWe found no additional maternal or neonatal risks of using antidepressants prescribed to women with hypertension disorders during pregnancy.

Indexed as

Antidepressive AgentsBirth WeightHypertension, Pregnancy-InducedAdultAntihypertensive AgentsApgar ScoreFemaleHumansInfant, NewbornIntensive Care Units, NeonatalNetherlandsPregnancyPregnancy Complications, CardiovascularPregnancy OutcomeRetrospective StudiesAntidepressive AgentsAntihypertensive AgentsAntidepressantsHypertension in pregnancyRetrospective cohort study

Identifiers

PMID38286817
OpenAlexW4391308952

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.