ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024
MiR-17-5p-engineered sEVs Encapsulated in GelMA Hydrogel Facilitated Diabetic Wound Healing by Targeting PTEN and p21.
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Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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0cells of the map it votes in
48citing papers in PubMed
15.7field-weighted citation impact, top 1% of its field
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
48 citing papers in PubMed, 63 citations in OpenAlex.
- HDAC1 maintains metabolic homeostasis in nucleus pulposus cells via post-translational modification interactions with YBX1.Experimental & molecular medicine · 2026Article
- Salidroside-loaded stem cell-derived artificial nanovesicles in hydrogel microneedles alleviate inflammation and enhance diabetic wound regeneration.Materials today. Bio · 2026Article
- Extracellular vesicle-based delivery systems for nucleic acid therapeutics.Molecular therapy. Nucleic acids · 2026Review
- Engineered small extracellular vesicles as bioactive materials: Integrating engineering strategies for cargo loading and targeted delivery systems.Bioactive materials · 2026Review
- Injectable ROS-scavenging and NIR-responsive nanocomposite hydrogel for staphylococcus aureus-infected diabetic wound healing.Journal of nanobiotechnology · 2026Article
- Hydrogel-extracellular vesicle engineering delivery system: a promising therapeutic strategy for wound healing.Journal of nanobiotechnology · 2026Review
- Bacterial extracellular vesicles as bioactive nanocarriers for wound treatment.Acta pharmaceutica Sinica. B · 2026Review
- Microneedle-mediated delivery of Coptis chinensis-derived nanovesicles orchestrating antibacterial and macrophage reprogramming for comprehensive wound healing.Journal of nanobiotechnology · 2026Article
- Mitochondrial protein-enriched artificial nanovesicles: mitochondrial recovery and antioxidation for diabetic wound treatment.Journal of nanobiotechnology · 2026Article
- DNA-Inspired Multi-Functional Double-Cross-Linking Self-Healing Hydrogel Promotes the Healing of Diabetic Wounds.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Recent advances and challenges in hydrogel-based delivery of immunomodulatory strategies for diabetic wound healing.Theranostics · 2026Review
- Multimodal Bioactive Approaches in Smart Dressings for Diabetic Foot Ulcers.International journal of nanomedicine · 2026Review
- Advanced small extracellular vesicles delivery systems forExtracellular vesicles and circulating nucleic acids · 2026Review
- Tideglusib-Preactivated Osteoblasts Encapsulated in Ceramic Particle-Reinforced GelMA Hydrogel for Enhanced Critical-Size Bone Defect Regeneration.Drug design, development and therapy · 2026Article
- Synergistic effects of berberine and adipose stem cells in a silk fibroin-PEG hydrogel for diabetic wound healing via macrophage polarization modulation.Regenerative biomaterials · 2026Article
- Hydrogel Microspheres for Biomedical Applications.Small science · 2026Review
- Exosome-Biomaterial Platforms for Diabetic Skin Infections: Microenvironment Remodeling, Responsive Delivery, and Clinical Translation.International journal of nanomedicine · 2026Review
- Open Porous Microenvironment-regulatory Microspheres Loaded with Curcumin@BSA NPs/BMSCs for Diabetic Wound Treatment.Theranostics · 2026Article
- Mesenchymal stem cell-derived small extracellular vesicles-loaded GelMA microspheres enhance diabetic wound healing by promoting M2 macrophage polarization through p38 MAPK inhibition.Materials today. Bio · 2025Article
- Omentin-1 promotes wound healing in diabetic mice by improving vascular endothelial cell function.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
15 authors at 2 institutions in 2 countries.
Qian WeiResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, 100048, P. R. China.
Jianlong SuResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, 100048, P. R. China.
Sheng MengResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, 100048, P. R. China.
Yaxi WangResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, 100048, P. R. China.
Kui MaResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, 100048, P. R. China.
Bingmin LiResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, 100048, P. R. China.
Ziqiang ChuResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, 100048, P. R. China.
Qilin HuangResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, 100048, P. R. China.
Wenzhi HuResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, 100048, P. R. China.
Zihao WangResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, 100048, P. R. China.
Lige TianResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, 100048, P. R. China.
Xi LiuResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, 100048, P. R. China.
Tanshi LiResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, 100048, P. R. China.
Xiaobing FuResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, 100048, P. R. China.
Cuiping ZhangResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, 100048, P. R. China.ORCID 0000-0003-0320-6226
Chinese PLA General Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN
Funding
1.3.5 Project for Disciplines of Excellence, West China Hospital, Sichuan University ZYGD22008CAMS Innovation Fund for Medical Sciences CIFMS 2019-I2M-5-059Military Medical Research Projects 2022-JCJQ-ZB-09600Military Medical Research Projects 2023-JSKY-SSQG-006National Key Research and Development Programs of China 2022YFA1104303National Nature Science Foundation of China 22205260National Nature Science Foundation of China 81830064National Nature Science Foundation of China 82172211National Nature Science Foundation of China 92268206Natural Science Foundation of Beijing 7242129
Abstract
Delayed wound healing is a major complication of diabetes, and is associated with impaired cellular functions. Current treatments are unsatisfactory. Based on the previous reports on microRNA expression in small extracellular vesicles (sEVs), miR-17-5p-engineered sEVs (sEVs
Indexed as
Diabetes MellitusExtracellular VesiclesGelatinMethacrylatesMicroRNAsWound HealingDiabetes ComplicationsEndothelial CellsGlucoseHumansHydrogelsProto-Oncogene Proteins p21(ras)PTEN PhosphohydrolaseGelatingelatin methacryloylGlucoseHydrogelsMethacrylatesMicroRNAsMIRN17 microRNA, humanProto-Oncogene Proteins p21(ras)PTEN PhosphohydrolasePTEN protein, humanangiogenesiscollagen depositiondiabetic woundsmiR‐17‐5psmall extracellular vesicles
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.