Evidence map›Paper›PMID 38286629›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Cumulative Effects of Resting-State Connectivity Across All Brain Networks Significantly Correlate with Attention-Deficit Hyperactivity Disorder Symptoms.

Michael A Mooney, Robert J M Hermosillo, Eric Feczko, Oscar Miranda-Dominguez, Lucille A Moore, Anders Perrone, Nora Byington, Gracie Grimsrud, Amanda Rueter, Elizabeth Nousen and 5 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Big data and psychiatry: advances, constraints and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
    Article
  3. Article
  4. Investigating the Shared and Divergent Neuroanatomical Features of Attentional Deficits in Adolescents.Journal of the American Academy of Child and Adolescent Psychiatry · 2026
    Article
  5. Review
  6. The Evolving ADHD Phenotype in the Externalizing Context.The American journal of psychiatry · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Harnessing mega-analysis in the era of "big data" neuroimaging.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  15. Review
  16. Considerations toward an epigenetic and common pathways theory of mental disorder.Journal of psychopathology and clinical science · 2023
    Article
  17. Article
  18. Evidence from "big data" for the default-mode hypothesis of ADHD: a mega-analysis of multiple large samples.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Michael A MooneyDivision of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, Oregon 97239 mooneymi@ohsu.edu.ORCID 0000-0003-1372-8722
Robert J M HermosilloDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55454.
Eric FeczkoDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55454.
Oscar Miranda-DominguezDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55454.
Lucille A MooreDepartment of Neurology, Oregon Health & Science University, Portland, Oregon 97239.
Anders PerroneMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, Minnesota 55414.
Nora ByingtonMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, Minnesota 55414.
Gracie GrimsrudMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, Minnesota 55414.
Amanda RueterMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, Minnesota 55414.
Elizabeth NousenCenter for Mental Health Innovation, Oregon Health & Science University, Portland, Oregon 97239.
Dylan AntovichDivision of Psychology, Department of Psychiatry, Oregon Health & Science University, Portland, Oregon 97239.
Sarah W Feldstein EwingDepartment of Psychology, University of Rhode Island, Kingston, Rhode Island 02881.
Bonnie J NagelCenter for Mental Health Innovation, Oregon Health & Science University, Portland, Oregon 97239.
Joel T NiggCenter for Mental Health Innovation, Oregon Health & Science University, Portland, Oregon 97239.
Damien A FairDepartment of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55454.
University of Minnesota · USOregon Health & Science University · USUniversity of Rhode Island · US

Funding

ABCD-USA Consortium: Coordinating CenterU24DA041147 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SANDRA A BROWN, TERRY L. JERNIGAN · 2015 to 2026
$54.7M
ABCD-USA Consortium: Data Analysis, Informatics and Resource CenterU24DA041123 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ANDERS M DALE · 2015 to 2026
$51.5M
Adolescent Substance Use Initiation: Disentangling neurocognitive risks from consequences using longitudinal and genetically-informed methodsU01DA041120 · NIDA · UNIVERSITY OF MINNESOTA · PI Monica Luciana, Sylia Wilson · 2015 to 2026
$34.5M
ABCD-USA Consortium: Research ProjectU01DA041089 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Joanna Jacobus, Susan F. Tapert · 2015 to 2026
$31.7M
Prospective Research Studies of Maturation (PRISM)- Research ProjectU01DA041134 · NIDA · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI ERIN MCGLADE, PERRY FRANKLIN RENSHAW · 2015 to 2026
$29.2M
ABCD-USA CONSORTIUM: RESEARCH PROJECTU01DA041048 · NIDA · CHILDREN'S HOSPITAL OF LOS ANGELES · PI Megan Marie Herting, ELIZABETH R SOWELL · 2015 to 2026
$28.7M
ABCD-USA Consortium: Research ProjectU01DA041106 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mary M Heitzeg, Chandra Sekhar Sripada · 2015 to 2026
$24.9M
FIU-ABCD: Pathways and Mechanisms to Addiction in the Latino Youth of South FloridaU01DA041156 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI Raul Gonzalez, Angela R Laird · 2015 to 2026
$22.8M
ABCD-USA Consortium: Research ProjectU01DA041148 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Damien A Fair, Rebekah S Huber · 2015 to 2026
$22.3M
ABCD-USA: NYC Research ProjectU01DA041174 · NIDA · YALE UNIVERSITY · PI Arielle Ryan Baskin-Sommers, Betty J Casey · 2015 to 2026
$19.7M
Adolescent Brain Cognitive Development (ABCD) Prospective Research in Studies of Maturation (PRISM) ConsortiumU01DA041117 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI LINDA CHANG, THOMAS M ERNST · 2015 to 2026
$19.5M
15/21 ABCD-USA Consortium: Research Project Site at LIBRU01DA050989 · NIDA · LAUREATE INSTITUTE FOR BRAIN RESEARCH · PI ROBIN L AUPPERLE, MARTIN P. PAULUS · 2020 to 2026
$14.7M
NIDA NIH HHS U01 DA041022NIDA NIH HHS U01 DA041025NIDA NIH HHS U01 DA041028NIDA NIH HHS U01 DA041048NIDA NIH HHS U01 DA041089NIDA NIH HHS U01 DA041093NIDA NIH HHS U01 DA041106NIDA NIH HHS U01 DA041117NIDA NIH HHS U01 DA041120NIDA NIH HHS U01 DA041134NIDA NIH HHS U01 DA041148NIDA NIH HHS U01 DA041156NIDA NIH HHS U01 DA041174NIDA NIH HHS U01 DA050987NIDA NIH HHS U01 DA050988NIDA NIH HHS U01 DA050989NIDA NIH HHS U01 DA051016NIDA NIH HHS U01 DA051018NIDA NIH HHS U01 DA051037NIDA NIH HHS U01 DA051039NIDA NIH HHS U24 DA041123NIDA NIH HHS U24 DA041147NIMH NIH HHS R01 MH115357NIMH NIH HHS R01 MH131685NIMH NIH HHS R37 MH059105
6 · The paper itself

Abstract

Identification of replicable neuroimaging correlates of attention-deficit hyperactivity disorder (ADHD) has been hindered by small sample sizes, small effects, and heterogeneity of methods. Given evidence that ADHD is associated with alterations in widely distributed brain networks and the small effects of individual brain features, a whole-brain perspective focusing on cumulative effects is warranted. The use of large, multisite samples is crucial for improving reproducibility and clinical utility of brain-wide MRI association studies. To address this, a polyneuro risk score (PNRS) representing cumulative, brain-wide, ADHD-associated resting-state functional connectivity was constructed and validated using data from the Adolescent Brain Cognitive Development (ABCD,

Indexed as

Attention Deficit Disorder with HyperactivityAdolescentAdultBrainBrain MappingChildCognitionFemaleHumansMagnetic Resonance ImagingMaleNeural PathwaysReproducibility of ResultsYoung Adultattention-deficit hyperactivity disorderbrain-wide association studyMRIpolygenic scorepolyneuro scoreresting-state functional connectivity

Identifiers

PMID38286629
PMCPMC10919250
OpenAlexW4391305462

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.