Evidence map›Paper›PMID 38286415›Full record

ArticleJournal of sleep research2025

Gender differences in the relationship between sleep and age in a Brazilian cohort: the Baependi Heart Study.

Tâmara P Taporoski, Felipe Beijamini, Shaina Alexandria, David Aaby, Malcolm von Schantz, Alexandre C Pereira, Kristen L Knutson

Open access · hybridAbstract read
In one paragraph

Article in Journal of sleep research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Sleep as the Foundation of Brain Health.Seminars in neurology · 2025
    Review
  8. Article
  9. Sleep Health in Human Biology Research.American journal of human biology : the official journal of the Human Biology Council · 2025
    Article
  10. Robust Metabolomic Age Prediction Based on a Wide Selection of Metabolites.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  11. Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Tâmara P TaporoskiFeinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0001-8783-4013
Felipe BeijaminiFederal University of Fronteira Sul, Realeza, Brazil.ORCID 0000-0002-8632-2101
Shaina AlexandriaFeinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0002-3069-4299
David AabyFeinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0002-2395-3563
Malcolm von SchantzFaculty of Health and Life Sciences, Northumbria University, Newcastle Upon Tyne, UK.ORCID 0000-0002-9911-9436
Alexandre C PereiraIncor, University of São Paulo School of Medicine, São Paulo, Brazil.ORCID 0000-0002-7782-5540
Kristen L KnutsonFeinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0002-2751-6168
Northwestern University · USBrigham and Women's Hospital · USNorthumbria University · GBUniversidade Federal da Fronteira Sul · BR

Funding

Leveraging a Unique existing Cohort to elucidate the Link between sleep and cardio-metabolic diseaseR01HL141881 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KNUTSON, KRISTEN · 2019 to 2022
$2.7M
NHLBI NIH HHS R01 HL141881NHLBI NIH HHS R01HL141881
6 · The paper itself

Abstract

Gender and age are well-established determinants of health and sleep health that influence overall health, which also often varies by gender and age. Sleep architecture is an important component of sleep health. The goal of this analysis was to examine whether associations between age and sleep stages differ by gender in the absence of moderate-severe obstructive sleep apnea (OSA) in a rural setting in Brazil. This study conducted polysomnography recordings in the Baependi Heart Study, a cohort of Brazilian adults. Our sample included 584 women and 309 men whose apnea-hypopnea index was ≤15 events/h. We used splines to distinguish non-linear associations between age, total sleep time, wake after sleep onset (WASO), N2, N3, and rapid-eye-movement sleep. The mean (standard deviation; range) age was 47 (14; 18-89) years. All sleep outcomes were associated with age. Compared to men, women had more N3 sleep and less WASO after adjusting for age. Model-based comparisons between genders at specific ages showed statistically higher mean WASO for men at ages 60 (+13.6 min) and 70 years (+19.5 min) and less N3 for men at ages 50 (-13.2 min), 60 (-19.0 min), and 70 years (-19.5 min) but no differences at 20, 30, 40 or 80 years. The other sleep measures did not differ by gender at any age. Thus, even in the absence of moderate-severe OSA, sleep architecture was associated with age across adulthood, and there were gender differences in WASO and N3 at older ages in this rural community.

Indexed as

SleepSleep StagesAdolescentAdultAgedAged, 80 and overAge FactorsBrazilCohort StudiesFemaleHumansMaleMiddle AgedPolysomnographySex FactorsSleep Apnea, Obstructiveageinggender characteristicssleep qualityslow‐wave sleep

Identifiers

PMID38286415
PMCPMC11284249
OpenAlexW4391329023

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.