Evidence map›Paper›PMID 38285639›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2024

Longitudinal Associations Between Multimorbidities and Patient-Reported Quality of Life.

Eileen K Graham, Olivia E Atherton, Daniel K Mroczek, Chloe McGhee, Lily Pieramici, Marquita Lewis-Thames, Laura Curtis, David Cella, Lauren Opsasnick, Rebecca Lovett and 2 more

Abstract read
In one paragraph

Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Implementation science in care for older adults across healthcare settings: a scoping review.Archives of public health = Archives belges de sante publique · 2026
    Pooled it
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Eileen K GrahamDepartment of Medical Social Sciences, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0003-3095-4625
Olivia E AthertonDepartment of Psychology, University of Houston, Houston, Texas, USA.
Daniel K MroczekDepartment of Medical Social Sciences, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0003-3748-5059
Chloe McGheeDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.
Lily PieramiciDepartment of Psychology, Northwestern University, Evanston, Illinois, USA.
Marquita Lewis-ThamesDepartment of Medical Social Sciences, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0001-5909-7167
Laura CurtisDivision of General Internal Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.
David CellaDepartment of Medical Social Sciences, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0002-9881-4541
Lauren OpsasnickDivision of General Internal Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.
Rebecca LovettDivision of General Internal Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.
Rachel O'ConorDivision of General Internal Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.
Michael S WolfDepartment of Medical Social Sciences, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.

Funding

Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI MILDA Renne SAUNDERS · 2011 to 2026
$10.0M
The Claude D. Pepper Older Americans Independence Center (OAIC) at Northwestern UniversityP30AG059988 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ACKERMANN, RONALD T. · 2020 to 2024
$7.1M
Improving adherence to posttreatment follow-up care for rural lung cancer survivors through a community-clinical survivorship care team modelK01CA262342 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEWIS, MARQUITA W. · 2021 to 2025
$801k
Management of Complex Medication Regimens among Older Adults with Alzheimer's Disease and Related Dementias and their CaregiversK01AG070107 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI O'CONOR, RACHEL · 2021 to 2025
$685k
NCI NIH HHS K01 CA262342NIA NIH HHS K01 AG070107NIA NIH HHS P30 AG059988NIA NIH HHS P30AG059988NIDDK NIH HHS P30 DK092949
6 · The paper itself

Abstract

objectivesThe global prevalence of multimorbidity is increasing as the population ages. As individuals get older, they are likely to develop multiple chronic conditions, and nearly two-thirds of older adults in the United States are estimated to experience 2 or more chronic conditions. The present preregistered study examined whether multimorbidity was associated with longitudinal changes in health-related quality of life (i.e., anxiety, depression, and physical function) and whether these associations were moderated by sociodemographic factors (i.e., sex, race, marital status, income, insurance, and education).

methodsData come from the Health Literacy and Cognitive Function Among Older Adults Longitudinal Study (LitCog), a prospective cohort study of English-speaking older adults (N = 900). At each measurement occasion, participants reported anxiety, depression, and physical function using the Patient Reported Outcomes Information System, chronic conditions, and sociodemographic characteristics. We employed multilevel growth models to estimate changes in health-related quality of life, with multimorbidities as a predictor and sociodemographics as covariates.

resultsResults indicated that individuals with multiple chronic conditions reported persistently high levels of anxiety and depression, and worse physical function. We found evidence for racial health disparities, such that individuals who identified as non-White experienced worse health-related quality of life as multimorbidities increased, relative to White participants. DISCUSSION: These results contribute to the current conversation about the long-term impacts of structural and systemic barriers experienced by minoritized groups. We further discuss the public health implications of multimorbidity in older adulthood.

Indexed as

Multiple Chronic ConditionsQuality of LifeAgedChronic DiseaseHumansLongitudinal StudiesMultimorbidityPatient Reported Outcome MeasuresProspective StudiesUnited StatesAnxietychronic conditionsdepressionpatient-reported outcomesphysical function

Identifiers

PMID38285639
PMCPMC10824385

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.