ArticleJMIR public health and surveillance2024
Global Trends in the Incidence of Anxiety Disorders From 1990 to 2019: Joinpoint and Age-Period-Cohort Analysis Study.
Article in JMIR public health and surveillance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Early interventions for first onset of symptoms of mental health conditions: an umbrella review of systematic reviews.BMC medicine · 2026Pooled it
- Cerina-Cognitive Behavioral Therapy-Based Mobile App for Managing Generalized Anxiety Disorder Symptoms Among University Students: Results From a Pilot Feasibility Randomized Controlled Trial.JMIR mHealth and uHealth · 2025Trial
- The Relationship between subjectively perceived life events and social anxiety among adolescents in Southwest China: the chain mediating effects of fear of negative evaluation and body shame.BMC public health · 2026Article
- Developmental Impacts of PANS/PANDAS and Inadequate Support for Children and Families.Child psychiatry and human development · 2026Article
- Global, regional, and national burdens of anxiety disorders among older adults, 1990-2021: A systematic analysis for the Global Burden of Diseases Study 2021.Social psychiatry and psychiatric epidemiology · 2026Article
- Sweetening fear exposure: study protocol for a multi-day, randomized controlled trial to study effects of glucose in exposure sessions of participants with public speaking anxiety.BMC psychology · 2026Article
- Generational differences in mental health and drivers of youth mental health decline in Australia and the United Kingdom.Frontiers in public health · 2026Article
- Revisiting the Proximal Dominance Assumption: Community Social Inclusion in an Ecological Analysis of Finnish Adolescent Mental Health.Psychology research and behavior management · 2026Article
- Mental Health Experiences and Challenges Among Individuals with Myasthenia Gravis: Insights from Patient-Centered, Qualitative Analyses.Advances in therapy · 2025Review
- Global, regional and national burden of asthma attributable to metabolic diseases from 1990 to 2021 and projected trends to 2040.BMC pulmonary medicine · 2025Article
- Emergency medicine: a global perspective on its past, evolution, and future.Internal and emergency medicine · 2025Article
- Anxiety in Portugal: Associated Factors in Adult Population from 2011 to 2021.Journal of clinical medicine · 2025Article
- Knowledge of mental disorders in primary healthcare nurses in the Western Cape, South Africa.Curationis · 2025Article
- Incidence and prevalence of dysthymia among young adults in China, 1990-2021, with forecasts to 2046: an age-period-cohort analysis of the Global Burden of Disease Study 2021.BMC psychiatry · 2025Article
- Effects of otolaryngological diseases on sleep quality, anxiety, and depression: a multicenter observational study.BMC psychiatry · 2025Observational
- Global trends and inequalities in the burden of drug use disorders: a comprehensive analysis from 1990 to 2021 with future projections.Frontiers in public health · 2025Article
- Dynamic changes and future trend predictions of the global burden of anxiety disorders: analysis of 204 countries and regions from 1990 to 2021 and the impact of the COVID-19 pandemic.EClinicalMedicine · 2025Article
- Trends in incidence, prevalence, and disability-adjusted life years of schizophrenia in China from 1990 to 2021, with projections for 2022-2050.Frontiers in psychiatry · 2025Article
- A generational relational model of nature and mental wellbeing: results of a qualitative analysis.Frontiers in psychology · 2025Article
- Global burden of hearing loss in people aged 60 years and older, 1990-2021: results from the global burden of disease study.Frontiers in public health · 2025Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnxiety disorders (ADs) are the most common mental illness with high prevalence, chronicity, and comorbidity. Despite rapid economic and cultural development, the global incidence of ADs continues to increase, with predominance in male individuals.
objectiveTo address the above issues, we analyzed the dynamic trends of the global incidence and disease burden of ADs from 1990 to 2019 and their different effects on age, period, and birth cohort and predicted the future trend of AD incidence.
methodsThe data were obtained from the Global Burden of Disease study in 2019. A joinpoint regression model was used to calculate the annual percent change in AD incidence, and age-period-cohort analysis was used to estimate the independent effects of age, period, and cohort. Nordpred age-period-cohort analysis was used to predict the incidence of ADs from 2020 to 2044.
resultsThe age-standardized incidence rate of ADs increased by 1.06% for both sexes, and the age-standardized disability-adjusted life-year (DALY) rate (ASDR) decreased by 0.12%. Joinpoint regression indicated that increments in average annual percent changes in the age-standardized incidence rate (0.068 vs 0.012) and ASDR (0.035 vs -0.015) for ADs globally were higher among male individuals than female individuals. The age-period-cohort analyses revealed that the relative risk (RR) of the incidence and DALYs of ADs among people of different sexes increased with age in adolescence and middle age and then decreased. For the period effect, the RR of incidence decreased, whereas the RR of DALYs increased in both sexes. Moreover, the RR of the incidence gradually increased and DALYs slowly decreased with birth year for both male and female individuals. New cases of ADs in male individuals are predicted to increase in the coming 25 years.
conclusionsThis study provided the changing trend of the global incidence and disease burden of ADs in the past 3 decades, indicating that early prevention and effective control cannot be ignored. We analyzed the age-period-cohort effect of potential trends in ADs and predicted future incidence trends. The results suggest that we should take active intervention measures, focusing on high-risk groups and developing effective management and control policies to reduce the global burden of disease.
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