Evidence map›Paper›PMID 38285359›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2024

Protocol of Geometric Morphometrics for Teratogenicity Testing.

Mariana Caipira Lei, Luís Félix, Carlos Venâncio

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mariana Caipira LeiAnimal and Veterinary Department, University Institute of Health Sciences, CESPU, CRL, Gandra, Portugal. mariana.lei@iucs.cespu.pt.
Luís FélixCenter for the Research and Technology of Agro-Environment and Biological Sciences (CITAB), UTAD, Vila Real, Portugal.
Carlos VenâncioCenter for the Research and Technology of Agro-Environment and Biological Sciences (CITAB), UTAD, Vila Real, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Geometric morphometrics (GM) enables a quantitative study of shapes and forms allowing the identification and characterization of teratogenic malformations. The GM methodology offers several advantages in comparison to traditional biometric methods, such as higher detail and precision analysis. In this chapter, we describe the recent application of the Procrustes method with ImageJ and MorphoJ programs in the characterization of developmental malformations. With this methodology, we are a step closer to being able to assign molecular pathways or unique signatures to a specific teratogen according to the produced phenotypes or to cluster unknown compounds.

Indexed as

ColeopteraTeratogenesisAnimalsPhenotypeTeratogensTeratogensDevelopmental periodEmbryonic morphologyLandmarksMorphometric analysisProcrustes methodStatistical calculationTeratogenic malformations

Identifiers

PMID38285359

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.