ArticleJournal of nephrology2024
Blood transfusion reactions and risk of acute kidney injury and major adverse kidney events.
Article in Journal of nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of acute kidney injury in Mexico; a systematic review and meta-analysis of pre-pandemic reports.Renal failure · 2025Pooled it
- Research Progress on Risk Factors for Acute Kidney Injury After Antibiotic-Loaded Bone Cement Spacer Treatment for Periprosthetic Joint Infection.Orthopaedic surgery · 2026Review
- Nomogram prediction of acute kidney injury following modified Morrow myectomy in hypertrophic obstructive cardiomyopathy: insights from 12 years of outcomes.BMC cardiovascular disorders · 2026Article
- Impact of post-transfusion hemoglobin levels on survival in critically Ill patients: a machine learning-based causal inference analysis.Scientific reports · 2026Article
- Predictive value of oxygen delivery and regional oxygen saturation during cardiopulmonary bypass for cardiac surgery-associated acute kidney injury in neonates with congenital heart disease.American journal of translational research · 2026Article
- Analysis of influencing factors for 5-year transfusion-related adverse events in a tertiary hospital using real-world data.Frontiers in medicine · 2026Article
- Does retrograde autologous priming during coronary artery bypass grafting reduce blood transfusions?JTCVS open · 2025Article
- Perioperative Red Blood Cell Transfusion and Long-Term Mortality in Coronary Artery Bypass Grafting: On-Pump and Off-Pump Analysis.Journal of clinical medicine · 2025Article
- Real-time blood gas management: evaluating quantum perfusion system's accuracy against a standard blood gas analysis in CPB.Journal of cardiothoracic surgery · 2025Article
- Transfusion Thresholds and Risk Factors of Acute Kidney Injury in Gastrointestinal Oncology Surgery: Insights from a Retrospective Study.Healthcare (Basel, Switzerland) · 2025Article
- Temporal Rule Mining for Enhanced Risk Pattern Extraction: A Case Study with Acute Kidney Injury.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2025Article
- Prognostic Scores for Acute Kidney Injury in Critically Ill Patients.Nursing reports (Pavia, Italy) · 2024Article
- Risk factors of renal function deterioration after radical nephroureterectomy for upper tract urothelial carcinoma.Frontiers in oncology · 2024Article
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21 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundBlood transfusion reactions may have a negative impact on organ function. It is unknown whether this association holds true for acute kidney injury (AKI). Therefore, we conducted a cohort study to assess the association between transfusion reactions and the incidence of AKI and major adverse kidney events.
methodsIn this retrospective cohort study, we included patients who received transfusion of blood products during hospitalization at the Hospital Civil of Guadalajara. We analyzed them according to the development of transfusion reactions, and the aim was to assess the association between transfusion reactions and AKI during long-term follow-up.
resultsFrom 2017 to 2021, 81,635 patients received a blood product transfusion, and 516 were included in our study. The most common transfusion was red blood cell packaging (50.4%), fresh frozen plasma (28.7%) and platelets (20.9%); of the 516 patients, 129 (25%) had transfusion reactions. Patients who had transfusion reactions were older and had more comorbidities. The most common type of transfusion reaction was allergic reaction (70.5%), followed by febrile nonhemolytic reaction (11.6%) and anaphylactoid reaction (8.5%). Most cases were considered mild. Acute kidney injury was more prevalent among those who had transfusion reactions (14.7%) than among those who did not (7.8%), p = < 0.01; those with AKI had a higher frequency of diabetes, vasopressors, and insulin use. Transfusion reactions were independently associated with the development of AKI (RR 2.1, p = < 0.02). Major adverse kidney events were more common in those with transfusion reactions. The mortality rate was similar between subgroups.
conclusionIn our retrospective cohort of patients who received blood product transfusions, 25% experienced transfusion reactions, and this event was associated with a twofold increase in the probability of developing AKI and some of the major adverse kidney events during long follow-up.
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