ArticleAbdominal radiology (New York)2024
Comparison and optimization of b value combinations for diffusion-weighted imaging in discriminating hepatic fibrosis.
Article in Abdominal radiology (New York), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 5 citations in OpenAlex.
- Diagnosis of liver fibrosis degree in autoimmune liver disease by magnetic resonance diffusion-weighted imaging.Abdominal radiology (New York) · 2026Article
- Evaluation of liver fibrosis using diffusion-weighted virtual magnetic resonance elastography and ultrasound elastography.Abdominal radiology (New York) · 2026Article
- [Advances and challenges in new technologies for imaging evaluation of liver fibrosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025Review
- Current Update on DWI-MRI and Its Radiomics in Liver Fibrosis-A Review of the Literature.Tomography (Ann Arbor, Mich.) · 2025Review
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10 authors at 3 institutions in 1 country.
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Abstract
INTRODUCTION AND
objectivesDiffusion-weighted imaging (DWI) has shown potential in characterizing hepatic fibrosis. However, there are no widely accepted apparent diffusion coefficient (ADC) values for the b value combination. This study aims to determine the optimal high and low b values of DWI to assess hepatic fibrosis in patients with chronic liver disease. MATERIALS AND
methodsThe prospective study included 81 patients with chronic liver disease and 21 healthy volunteers who underwent DWI, Magnetic resonance elastography (MRE), and liver biopsy. The ADC was calculated by twenty combinations of nine b values (0, 50, 100, 150, 200, 800, 1000, 1200, and 1500 s/mm
resultsAll ADC values of the healthy volunteers were significantly higher than those of the hepatic fibrosis group (all P < 0.01). With the progression of hepatic fibrosis, ADC values significantly decreased in b value combinations (100 and 1000 s/mm
conclusionDWI offers an alternative to MRE as a useful imaging marker for detecting and staging hepatic fibrosis. Clinically, ADC values for b values ranging from 200-800 s/mm
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