Evidence map›Paper›PMID 38285125›Full record

ArticleThe Journal of membrane biology2024

Isolated Cardiac Ryanodine Receptor Function Varies Between Mammals.

Catherine Carvajal, Jiajie Yan, Alma Nani, Jaime DeSantiago, Xiaoping Wan, Isabelle Deschenes, Xun Ai, Michael Fill

Abstract read
In one paragraph

Article in The Journal of membrane biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Catherine CarvajalDepartment of Physiology & Biophysics, Section of Cellular Signaling, Rush University Medical Center, 1750 W. Harrison Avenue, Chicago, IL, 60612, USA.ORCID 0000-0002-6530-7850
Jiajie YanDepartment of Physiology & Biophysics, Section of Cellular Signaling, Rush University Medical Center, 1750 W. Harrison Avenue, Chicago, IL, 60612, USA.ORCID 0000-0003-2434-7175
Alma NaniDepartment of Physiology & Biophysics, Section of Cellular Signaling, Rush University Medical Center, 1750 W. Harrison Avenue, Chicago, IL, 60612, USA.
Jaime DeSantiagoDepartment of Physiology & Biophysics, Section of Cellular Signaling, Rush University Medical Center, 1750 W. Harrison Avenue, Chicago, IL, 60612, USA.
Xiaoping WanDepartment of Physiology & Cell Biology, College of Medicine, The Ohio State University, 333 W. 10Th Avenue, Columbus, OH, 43210, USA.
Isabelle DeschenesDepartment of Physiology & Cell Biology, College of Medicine, The Ohio State University, 333 W. 10Th Avenue, Columbus, OH, 43210, USA.ORCID 0000-0002-1812-7267
Xun AiDepartment of Physiology & Biophysics, Section of Cellular Signaling, Rush University Medical Center, 1750 W. Harrison Avenue, Chicago, IL, 60612, USA. Xun.Ai@osumc.edu.ORCID 0000-0003-0739-0286
Michael FillDepartment of Physiology & Biophysics, Section of Cellular Signaling, Rush University Medical Center, 1750 W. Harrison Avenue, Chicago, IL, 60612, USA. michael_fill@rush.edu.ORCID 0000-0002-6094-8296

Funding

Limiting Pathological Calcium Induced Calcium Release in HeartR01HL057832 · NHLBI · RUSH UNIVERSITY MEDICAL CENTER · PI FILL, MICHAEL, GILLESPIE, DIRK · 1997 to 2024
$9.0M
The Stress Response Kinase JNK and Alcohol Evoked Atrial FibrillationR01AA024769 · NIAAA · OHIO STATE UNIVERSITY · PI AI, XUN, CHEN, SUI RONG WAYNE · 2017 to 2021
$3.3M
Heart-platelet crosstalk: JNK, AF, and thrombogenesisR01HL146744 · NHLBI · RUSH UNIVERSITY MEDICAL CENTER · PI Xun Ai, Yuchi Han · 2019 to 2026
$3.2M
Atrial and blood JNK in Postoperative AFR01HL168728 · NHLBI · OHIO STATE UNIVERSITY · PI Xun Ai · 2023 to 2026
$2.7M
Local RyR2 ControlF31HL151059 · NHLBI · RUSH UNIVERSITY MEDICAL CENTER · PI CARVAJAL, CATHERINE · 2020 to 2021
$92k
NHLBI NIH HHS F31 HL151059NHLBI NIH HHS R01 HL057832NHLBI NIH HHS R01 HL146744NHLBI NIH HHS R01 HL168728NIAAA NIH HHS R01 AA024769NIH HHS F31HL151059NIH HHS R01AA024769NIH HHS R01HL057832
6 · The paper itself

Abstract

Concerted robust opening of cardiac ryanodine receptors' (RyR2) Ca

Indexed as

Myocytes, CardiacRyanodine Receptor Calcium Release ChannelAnimalsCalciumHeart VentriclesHumansMammalsMiceRabbitsRatsSarcoplasmic ReticulumCalciumRyanodine Receptor Calcium Release ChannelCalsequestrinCardiac muscleRyanodine receptorSarcoplasmic reticulum

Identifiers

PMID38285125
PMCPMC11299243

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.