Evidence map›Paper›PMID 38285098›Full record

ArticleAmino acids2024

Assessment of bioactive peptides derived from laminin-111 as prospective breast cancer-targeting agents.

Fernanda Ferreira Mendonça, Danielle Vieira Sobral, Ana Claudia Ranucci Durante, Ana Cláudia Camargo Miranda, Jorge Mejia, Daniele de Paula Faria, Fabio Luiz Navarro Marques, Marycel Figols de Barboza, Leonardo Lima Fuscaldi, Luciana Malavolta

Open access · goldAbstract read
In one paragraph

Article in Amino acids, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Fernanda Ferreira MendonçaDepartment of Physiological Sciences, Santa Casa de Sao Paulo School of Medical Sciences, Rua Dr. Cesareo Motta Jr. 61, Sao Paulo, CEP 01221-020, Brazil.
Danielle Vieira SobralDepartment of Physiological Sciences, Santa Casa de Sao Paulo School of Medical Sciences, Rua Dr. Cesareo Motta Jr. 61, Sao Paulo, CEP 01221-020, Brazil.
Ana Claudia Ranucci DuranteDepartment of Physiological Sciences, Santa Casa de Sao Paulo School of Medical Sciences, Rua Dr. Cesareo Motta Jr. 61, Sao Paulo, CEP 01221-020, Brazil.
Ana Cláudia Camargo MirandaHospital Israelita Albert Einstein, Sao Paulo, 05521-200, Brazil.
Jorge MejiaHospital Israelita Albert Einstein, Sao Paulo, 05521-200, Brazil.
Daniele de Paula FariaLaboratory of Nuclear Medicine (LIM-43), Department of Radiology and Oncology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, 01246-903, Brazil.
Fabio Luiz Navarro MarquesLaboratory of Nuclear Medicine (LIM-43), Department of Radiology and Oncology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, 01246-903, Brazil.
Marycel Figols de BarbozaHospital Israelita Albert Einstein, Sao Paulo, 05521-200, Brazil.
Leonardo Lima FuscaldiDepartment of Physiological Sciences, Santa Casa de Sao Paulo School of Medical Sciences, Rua Dr. Cesareo Motta Jr. 61, Sao Paulo, CEP 01221-020, Brazil.
Luciana MalavoltaDepartment of Physiological Sciences, Santa Casa de Sao Paulo School of Medical Sciences, Rua Dr. Cesareo Motta Jr. 61, Sao Paulo, CEP 01221-020, Brazil. luciana.malavolta@gmail.com.
Faculdade de Ciências Médicas da Santa Casa de São Paulo · BRHospital Israelita Albert Einstein · BRUniversidade de São Paulo · BR

Funding

Sao Paulo Research Foundation (FAPESP) 2021/08717-8
6 · The paper itself

Abstract

Breast cancer remains a pressing public health issue primarily affecting women. Recent research has spotlighted bioactive peptides derived from laminin-111, implicated in breast tumor development. Remarkably, the sequences IKVAV, YIGSR, and KAFDITYVRLKF from the α1, β1, and γ1 chains, respectively, have garnered significant attention. This study aims to assess the potential of these radiolabeled peptides as targeting agents for breast cancer. The three peptides were synthesized using the Fmoc strategy, purified via reversed-phase high-performance liquid chromatography (RP-HPLC), and characterized through mass spectrometry. Iodine-131 (

Indexed as

Breast NeoplasmsAnimalsFemaleHumansLamininPeptidesProspective StudiesTissue DistributionLamininPeptidesBreast cancerLaminin 111-derived peptidesRadiolabeled peptidesTargeting molecules

Identifiers

PMID38285098
PMCPMC10824877
OpenAlexW4391317018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.