Evidence map›Paper›PMID 38284801›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2024

Cross-national comparisons of later-life cognitive function using data from the Harmonized Cognitive Assessment Protocol (HCAP): Considerations and recommended best practices.

Lindsay C Kobayashi, Richard N Jones, Emily M Briceño, Miguel Arce Rentería, Yuan Zhang, Erik Meijer, Kenneth M Langa, Jinkook Lee, Alden L Gross

Open access · hybridAbstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Cognitive assessment tools for Arabic-speaking older adults: A systematic review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Pooled it
  2. Article
  3. Aging with dual burdens: cross-national evidence on mortality among older Hispanic adults with diabetes and dementia.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
  4. Article
  5. The association between lifetime marital histories and later-life cognitive function: evidence from the United States and China.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
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  14. Article
  15. Review
  16. Article
  17. Recommended best practices for construct-centered adaptation of the Harmonized Cognitive Assessment Protocol.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
  18. Missing data and imputation in the international studies following the Harmonized Cognitive Assessment Protocol.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Lindsay C KobayashiDepartment of Epidemiology, Center for Social Epidemiology and Population Health, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.ORCID 0000-0003-2725-3107
Richard N JonesDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA.
Emily M BriceñoDepartment of Physical Medicine & Rehabilitation, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Miguel Arce RenteríaTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University College of Physicians and Surgeons, New York City, New York, USA.
Yuan ZhangDepartment of Sociomedical Sciences, Columbia University, New York City, New York, USA.
Erik MeijerCenter for Economic and Social Research, University of Southern California, Los Angeles, California, USA.
Kenneth M LangaSurvey Research Center, University of Michigan Institute for Social Research, Ann Arbor, Michigan, USA.
Jinkook LeeCenter for Economic and Social Research, University of Southern California, Los Angeles, California, USA.
Alden L GrossDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
University of Michigan · USColumbia University · USUniversity of Southern California · USBrown University · USJohns Hopkins University · US

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Integrting Information About Aging SurveysR01AG030153 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Sara Adar, Alden L. Gross · 2007 to 2026
$41.7M
Leveraging a natural experiment to estimate the causal impact of blood sugar on dementia and cognition in IndiaR01AG051125 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jinkook Lee · 2015 to 2026
$26.8M
Health and Retirement Study: Harmonized Cognitive Assessment Protocol (HCAP)U01AG058499 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LANGA, KENNETH M · 2018 to 2023
$8.3M
Socioeconomic, Cardiovascular, and Psychosocial Sources of Cross-National Variation in Cognitive Health Among Older AdultsR01AG070953 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Alden L. Gross, Lindsay C Kobayashi · 2021 to 2026
$4.6M
Research Network for the Harmonized Cognitive Assessment Protocol (HCAP): Years 6-10U24AG065182 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lindsay C Kobayashi, KENNETH M LANGA · 2022 to 2026
$2.6M
Measurement of cognition and functional decline in Latinx older adults for detection of Alzheimer’s Disease and Related Dementias: A mixed-methods approachK23AG080035 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Emily Marie Briceno · 2023 to 2026
$767k
A cross-national comparative study on cardiometabolic risk, education, and cognitive agingR00AG070274 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ZHANG, YUAN S · 2023 to 2025
$721k
NIA NIH HHS K23 AG080035NIA NIH HHS R00 AG070274NIA NIH HHS R01 AG030153NIA NIH HHS R01 AG051125NIA NIH HHS R01 AG070953NIA NIH HHS U01 AG009740NIA NIH HHS U01 AG058499NIA NIH HHS U24 AG065182NIH HHS K23AG080035NIH HHS R00AG070274NIH HHS R01AG030153NIH HHS R01AG070953NIH HHS U24AG065182
6 · The paper itself

Abstract

The Harmonized Cognitive Assessment Protocol (HCAP) is a major innovation that provides, for the first time, harmonized data for cross-national comparisons of later-life cognitive functions that are sensitive to linguistic, cultural, and educational differences across countries. However, cognitive function does not lend itself to direct comparison across diverse populations without careful consideration of the best practices for such comparisons. This perspective discusses theoretical and methodological considerations and offers a set of recommended best practices for conducting cross-national comparisons of risk factor associations using HCAP data. Because existing and planned HCAP studies provide cognition data representing an estimated 75% of the global population ≥65 years of age, these recommended best practices will support high-quality comparative analyses of cognitive aging around the world. The principles described in this perspective are applicable to any researcher aiming to integrate or compare harmonized data on cognitive outcomes and their risk and protective factors across diverse populations.

Indexed as

CognitionHumansRisk Factorscognitive functioncognitive impairmentcross-cultural researchcross-national comparisonsharmonizationmeasurement

Identifiers

PMID38284801
PMCPMC10984496
OpenAlexW4391313905

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.