Evidence map›Paper›PMID 38284695›Full record

ArticleCurrent vascular pharmacology2024

Sedation with Ketamine-Propofol in Patients Undergoing Transcatheter Aortic Valve Implantation: A Comparative Retrospective Study on General Anesthesia.

Nurdan Yilmaz, Yasar Gokhan Gul, Murat Ugurlucan

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Current vascular pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nurdan YilmazDepartment of Anesthesiology and Reanimation, Medipol Mega University Hospital, Istanbul, Turkey.ORCID 0000-0003-4741-7877
Yasar Gokhan GulDepartment of Anesthesiology and Reanimation, Medipol Mega University Hospital, Istanbul, Turkey.ORCID 0000-0001-9531-4317
Murat UgurlucanDepartment of Cardiovascular Surgery, Biruni University Faculty of Medicine, Istanbul, Turkey.ORCID 0000-0001-6643-9364

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTranscatheter aortic valve implantation (TAVI) is used for patients with severe aortic stenosis who are at high risk for surgery. Since these patients are elderly and have comorbidities, their management is of great importance.

objectivesThis retrospective study compares two anesthesia techniques during TAVI: sedation (ketamine and propofol) and general anesthesia.

methodsPatients with severe aortic stenosis undergoing TAVI during 2021 in our hospital were retrospectively screened. Demographic data, comorbidities, anesthesia management, complications, and mortality of the patients were obtained from the records.

resultsThere were 137 patients treated with TAVI; 74 (54%) patients had sedation and 63 (46%) had general anesthesia. When the anesthesia management was evaluated, no significant difference in mortality was observed between the patients who received general anesthesia and sedation. After univariate and multivariate logistic regression analyses were performed to investigate factors having an impact on mortality, anemia (only in univariate analysis) in the whole study population was a statistically significant risk factor for mortality in patients undergoing TAVI (p<0.014).

conclusionThere was no significant difference in mortality in terms of anesthesia management. Anemia was a risk factor for mortality (only in univariate analysis) in the whole study population. We concluded that conscious sedation with ketamine and propofol is effective and safe for TAVI procedures compared to general anesthesia.

Indexed as

Anesthesia, GeneralAortic Valve StenosisKetamineProcedural SedationPropofolTranscatheter Aortic Valve ReplacementAgedAged, 80 and overAnemiaFemaleHumansHypnotics and SedativesMaleRetrospective StudiesRisk AssessmentRisk FactorsHypnotics and SedativesKetaminePropofolgeneral anesthesiaketaminepropofolsedationsevere aortic stenosis.Transcatheter aortic valve implantation (TAVI)

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.