Evidence map›Paper›PMID 38284551›Full record

ArticleJornal brasileiro de nefrologia

Relationship of hemoglobin levels with outcomes in deceased donor kidney transplant: a retrospective cohort study.

Beatriz Moreira Silva, Flavia Hosana Macedo, Enzo Eiji Miyasato Hayano, Suzeli Germano, Isabella Ferreira Ribeiro, Carolina Azze Franco, Lucio Requião, José Medina-Pestana, Miguel Angelo Goes

Open access · diamondAbstract read
In one paragraph

Article in Jornal brasileiro de nefrologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Beatriz Moreira SilvaUniversidade Federal de São Paulo, Divisão de Nefrologia, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-5735-406X
Flavia Hosana MacedoUniversidade Federal de São Paulo, Divisão de Nefrologia, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-5028-7976
Enzo Eiji Miyasato HayanoUniversidade Federal de São Paulo, Divisão de Nefrologia, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-1469-8441
Suzeli GermanoUniversidade Federal de São Paulo, Divisão de Nefrologia, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-3048-4240
Isabella Ferreira RibeiroUniversidade Federal de São Paulo, Divisão de Nefrologia, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-7593-2713
Carolina Azze FrancoUniversidade Federal de São Paulo, Departamento de Medicina, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-7206-4383
Lucio RequiãoUniversidade Federal de São Paulo, Divisão de Nefrologia, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-8751-9048
José Medina-PestanaUniversidade Federal de São Paulo, Divisão de Nefrologia, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-0750-7360
Miguel Angelo GoesUniversidade Federal de São Paulo, Divisão de Nefrologia, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-7687-3826
Universidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAnemia is frequent in patients undergoing replacement therapy for kidney failure. Anemia in the pre- and post-transplantation period might be related to kidney transplant outcomes. The current study therefore sought to assess the relationship between anemia, delayed allograft function (DGF), chronic kidney allograft dysfunction (CAD), and death from any cause following kidney transplantation from a deceased donor.

methodsThis was a retrospective study with 206 kidney transplant patients of deceased donors. We analyzed deceased donors' and kidney transplant patients' demographic data. Moreover, we compared biochemical parameters, anemia status, and medicines between DGF and non-DGF groups. Afterward, we performed a multivariate analysis. We also evaluated outcomes, such as CAD within one year and death in ten years.

resultsWe observed a lower frequency of pre-transplant hemoglobin concentration (Hb) but higher frequency of donor-serum creatinine and red blood transfusion within one week after transplantation in the group with DGF. In addition, there was an independent association between Hb concentration before transplantation and DGF [OR 0.252, 95%CI: 0.159-0.401; p < 0.001]. There was also an association between Hb concentration after six months of kidney transplantation and both CAD [OR 0.798, 95% CI: 0.687-0.926; p = 0.003] and death from any cause.

conclusionAn association was found between pre-transplantation anemia and DGF and between anemia six months after transplantation and both CAD and death by any cause. Thus, anemia before or after transplantation affects the outcomes for patients who have undergone kidney transplantation from a deceased donor.

Indexed as

AnemiaKidney TransplantationRenal InsufficiencyDelayed Graft FunctionGraft SurvivalHemoglobinsHumansRetrospective StudiesRisk FactorsTissue DonorsHemoglobins

Identifiers

PMID38284551
PMCPMC11210544
OpenAlexW4391253783

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.