Evidence map›Paper›PMID 38284236›Full record

ArticleJournal of dental research2024

Gli1

Y Deng, Q Li, K K H Svoboda, L A Opperman, L B Ruest, X Liu

Open access · greenAbstract read
In one paragraph

Article in Journal of dental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Targeting Gli1Stem cell reviews and reports · 2026
    Review
  2. Article
  3. Review
  4. Inflammation-triggered Gli1Cellular & molecular immunology · 2025
    Article
  5. Review
  6. Article
  7. Research progress of dental pulp regeneration treatment.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Y DengDepartment of Biomedical Sciences, Texas A&M University School of Dentistry, Dallas, TX, USA.
Q LiDepartment of Biomedical Sciences, Texas A&M University School of Dentistry, Dallas, TX, USA.
K K H SvobodaDepartment of Biomedical Sciences, Texas A&M University School of Dentistry, Dallas, TX, USA.
L A OppermanDepartment of Biomedical Sciences, Texas A&M University School of Dentistry, Dallas, TX, USA.
L B RuestDepartment of Biomedical Sciences, Texas A&M University School of Dentistry, Dallas, TX, USA.
X LiuDepartment of Biomedical Sciences, Texas A&M University School of Dentistry, Dallas, TX, USA.ORCID 0000-0003-0177-0886
The University of Texas at Dallas · US

Funding

MINE-MS for horizontal bone loss treatmentR01DE029808 · NIDCR · UNIVERSITY OF MISSOURI-COLUMBIA · PI LIU, XIAOHUA · 2021 to 2025
$1.8M
Chondrocyte-derived bone cells determine the overall pattern of TMJ condyle and contribute to bone remodelingR01DE025659 · NIDCR · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI RUEST, LOUIS-BRUNO · 2017 to 2021
$1.8M
NIDCR NIH HHS R01 DE025659NIDCR NIH HHS R01 DE029808
6 · The paper itself

Abstract

Periodontal mesenchymal stem cells (MSCs) play a crucial role in maintaining periodontium homeostasis and in tissue repair. However, little is known about how periodontal MSCs in vivo respond under periodontal disease conditions, posing a challenge for periodontium tissue regeneration. In this study, Gli1 was used as a periodontal MSC marker and combined with a Gli1-cre ERT2 mouse model for lineage tracing to investigate periodontal MSC fate in an induced periodontitis model. Our findings show significant changes in the number and contribution of Gli1

Indexed as

Mesenchymal Stem CellsPeriodontitisAnimalsMiceOsteogenesisPeriodontal LigamentPeriodontiumZinc Finger Protein GLI1Zinc Finger Protein GLI1alveolar bone lossbiomarkerscell lineageinflammationperiodonal diseaseregeneration

Identifiers

PMID38284236
PMCPMC11798346
OpenAlexW4391317446

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.