Evidence map›Paper›PMID 38283996›Full record

ArticleThe World Allergy Organization journal2024

Vernal keratoconjunctivitis and eosinophilic esophagitis: A rare combination?

Maria Cristina Artesani, Sara Urbani, Carla Riccardi, Mariacristina Esposito, Paola De Angelis, Francesca Rea, Renato Tambucci, Monica Malamisura, Luca Buzzonetti, Alessandro Giovanni Fiocchi

Abstract read
In one paragraph

Article in The World Allergy Organization journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Vernal keratoconjunctivitis: The burden of being allergic.The journal of allergy and clinical immunology. Global · 2025
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maria Cristina ArtesaniAllergy Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Sara UrbaniAllergy Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Carla RiccardiAllergy Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Mariacristina EspositoOphthalmology Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Paola De AngelisDigestive Endoscopy and Surgery Unit, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy.
Francesca ReaDigestive Endoscopy and Surgery Unit, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy.
Renato TambucciDigestive Endoscopy and Surgery Unit, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy.
Monica MalamisuraDigestive Endoscopy and Surgery Unit, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy.
Luca BuzzonettiOphthalmology Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Alessandro Giovanni FiocchiAllergy Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vernal keratoconjunctivitis (VKC) is a bilateral ocular inflammatory disease with a conjunctival and corneal involvement and typical onset during childhood. Eosinophilic esophagitis (EoE) is a chronic disease characterized by eosinophilic inflammation of the mucosa (≥15 eosinophils/HPF) and symptoms of esophageal dysfunction. EoE and VKC are both immune-mediated diseases sharing a similar pathogenetic mechanism and a high association with other allergic diseases. Nevertheless, no data are currently available about their clinical association. We present 4 cases of concomitant diagnosis of vernal keratoconjunctivitis and eosinophil esophagitis suggesting that these conditions may coexist in the same patient more frequently than expected. Health care providers should be aware of the possibility of co-occurrence in their daily practice.

Indexed as

AllergyEosinophilic esophagitisTh-2 diseaseVernal keratoconjunctivitis

Identifiers

PMID38283996
PMCPMC10821585

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.