Evidence map›Paper›PMID 38283929›Full record

ArticleArchives of medical sciences. Atherosclerotic diseases2023

The ins and outs of lipoprotein(a) assay methods.

Maryam Heydari, Majid Rezayi, Massimiliano Ruscica, Tannaz Jpamialahamdi, Thomas P Johnston, Amirhossein Sahebkar

Abstract read
In one paragraph

Article in Archives of medical sciences. Atherosclerotic diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maryam HeydariMedical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Majid RezayiMedical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Massimiliano RuscicaDepartment of Pharmacological and Biomolecular Science, Università degli Studi di Milano, Milan, Italy.
Tannaz JpamialahamdiApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Thomas P JohnstonDivision of Pharmacology and Pharmaceutical Science, School of Pharmacy, University of Missouri-Kansas City, Kansas City, MI, USA.
Amirhossein SahebkarApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathophysiological, epidemiological and genetic studies convincingly showed lipoprotein(a) (Lp(a)) to be a causal mediator of atherosclerotic cardiovascular disease (ASCVD). This happens through a myriad of mechanisms including activation of innate immune cells, endothelial cells as well as platelets. Although these certainties whether or not Lp(a) is ready for prime-time clinical use remain debated. Thus, remit of the present review is to provide an overview of different methods that have been employed for the measurement of Lp(a). The methods include dynamic light scattering, multi-angle light scattering analysis, near-field imaging, sedimentation, gel filtration, and electron microscopy. The development of multiple Lp(a) detection methods is vital for improved prediction of ASCVD risk.

Indexed as

apo(a)apo(a) size evaluationASCVDlipoprotein (a)Lp(a)

Identifiers

PMID38283929
PMCPMC10811544

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.