Evidence map›Paper›PMID 38283919›Full record

ReviewBiomaterials translational2023

Therapeutic potential of oncolytic viruses in the era of precision oncology.

Monchupa Kingsak, Thongpon Meethong, Jinnawat Jongkhumkrong, Li Cai, Qian Wang

Abstract readReview
In one paragraph

Review in Biomaterials translational, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Carrying passion in a numerical world.Biomaterials translational · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Monchupa KingsakDepartment of Chemistry and Biochemistry, University of South Carolina, Columbia, SC, USA.
Thongpon MeethongDepartment of Chemistry and Biochemistry, University of South Carolina, Columbia, SC, USA.
Jinnawat JongkhumkrongDepartment of Chemistry and Biochemistry, University of South Carolina, Columbia, SC, USA.
Li CaiDepartment of Chemistry, University of South Carolina Lancaster, Lancaster, SC, USA.
Qian WangDepartment of Chemistry and Biochemistry, University of South Carolina, Columbia, SC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oncolytic virus (OV) therapy has been shown to be an effective targeted cancer therapy treatment in recent years, providing an avenue of treatment that poses no damage to surrounding healthy tissues. Not only do OVs cause direct oncolysis, but they also amplify both innate and adaptive immune responses generating long-term anti-tumour immunity. Genetically engineered OVs have become the common promising strategy to enhance anti-tumour immunity, safety, and efficacy as well as targeted delivery. The studies of various OVs have been accomplished through phase I-III clinical trial studies. In addition, the uses of carrier platforms of organic materials such as polymer chains, liposomes, hydrogels, and cell carriers have played a vital role in the potentially targeted delivery of OVs. The mechanism, rational design, recent clinical trials, applications, and the development of targeted delivery platforms of OVs will be discussed in this review.

Indexed as

anti-cancerapplicationsdelivery platformgenetic modificationmechanismoncolytic virus

Identifiers

PMID38283919
PMCPMC10817786

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.