Evidence map›Paper›PMID 38283602›Full record

ArticleEvolutionary applications2024

Epigenetic changes to gene pathways linked to male fertility in ex situ black-footed ferrets.

Stavi R Tennenbaum, Robyn Bortner, Colleen Lynch, Rachel Santymire, Adrienne Crosier, Jenny Santiestevan, Paul Marinari, Budhan S Pukazhenthi, Pierre Comizzoli, Melissa T R Hawkins and 4 more

Abstract read
In one paragraph

Article in Evolutionary applications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Reproductive Sciences to the Rescue of Wild Animal Species.Advances in experimental medicine and biology · 2026
    Review
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Stavi R TennenbaumEcology and Evolutionary Biology Princeton University Princeton New Jersey USA.ORCID https://orcid.org/0000-0002-2547-6924
Robyn BortnerU.S. Fish & Wildlife Service National Black-Footed Ferret Conservation Center Carr Colorado USA.
Colleen LynchRiverbanks Zoo and Garden Columbia South Carolina USA.
Rachel SantymireBiology Department Georgia State University Atlanta Georgia USA.ORCID https://orcid.org/0000-0003-4102-9144
Adrienne CrosierCenter for Animal Care Sciences Smithsonian's National Zoo & Conservation Biology Institute Front Royal Virginia USA.ORCID https://orcid.org/0000-0003-3426-2650
Jenny SantiestevanCenter for Species Survival Smithsonian's National Zoo and Conservation Biology Institute Front Royal Virginia USA.
Paul MarinariCenter for Animal Care Sciences Smithsonian's National Zoo & Conservation Biology Institute Front Royal Virginia USA.
Budhan S PukazhenthiCenter for Species Survival Smithsonian's National Zoo and Conservation Biology Institute Front Royal Virginia USA.ORCID https://orcid.org/0000-0003-4657-2023
Pierre ComizzoliCenter for Species Survival Smithsonian's National Zoo and Conservation Biology Institute Front Royal Virginia USA.ORCID https://orcid.org/0000-0003-3079-9063
Melissa T R HawkinsDivision of Mammals, Department of Vertebrate Zoology National Museum of Natural History Washington DC USA.ORCID https://orcid.org/0000-0001-8929-1593
Jesús E MaldonadoCenter for Conservation Genomics Smithsonian's National Zoo and Conservation Biology Institute Washington DC USA.ORCID https://orcid.org/0000-0002-4282-1072
Klaus-Peter KoepfliCenter for Species Survival Smithsonian's National Zoo and Conservation Biology Institute Front Royal Virginia USA.ORCID https://orcid.org/0000-0001-7281-0676
Bridgett M vonHoldtEcology and Evolutionary Biology Princeton University Princeton New Jersey USA.ORCID https://orcid.org/0000-0001-6908-1687
Alexandra L DeCandiaCenter for Conservation Genomics Smithsonian's National Zoo and Conservation Biology Institute Washington DC USA.ORCID https://orcid.org/0000-0001-8485-5556

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Environmental variation can influence the reproductive success of species managed under human care and in the wild, yet the mechanisms underlying this phenomenon remain largely mysterious. Molecular mechanisms such as epigenetic modifiers are important in mediating the timing and progression of reproduction in humans and model organisms, but few studies have linked epigenetic variation to reproductive fitness in wildlife. Here, we investigated epigenetic variation in black-footed ferrets (

Indexed as

conservationDNA methylationinfertilityMustela nigripesreproductionsperm

Identifiers

PMID38283602
PMCPMC10818088

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.