ArticleEvolutionary applications2024
A cytochrome P450 insecticide detoxification mechanism is not conserved across the Megachilidae family of bees.
Article in Evolutionary applications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Species-specific brain transcriptomic responses to clothianidin and sulfoxaflor in pollinators.iScience · 2026Article
- Proof-of-concept engineering of Escherichia coli expressing a bee-derived cytochrome P450 monooxygenase for thiamethoxam detoxification.Journal of biological engineering · 2026Article
- Comparative lipidomic and proteomic analysis reveals species-specific differences in midgut composition and insecticide absorption between Apis mellifera and Bombus terrestris.Pest management science · 2026Article
- Complex Roles of Insect Cytochrome P450s in Chemical Adaptation.International journal of biological sciences · 2026Review
- Chromosome-Level Genome Assembly of the Leafcutter Bee Megachile rotundata Reveals Its Ecological Adaptation and Pollination Biology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A new exposure protocol adapted for wild bees reveals species-specific impacts of the sulfoximine insecticide sulfoxaflor.Ecotoxicology (London, England) · 2024Article
- The nuclear and mitochondrial genome assemblies of Tetragonisca angustula (Apidae: Meliponini), a tiny yet remarkable pollinator in the Neotropics.BMC genomics · 2024Article
- A cytochrome P450 insecticide detoxification mechanism is not conserved across the Megachilidae family of bees.Evolutionary applications · 2024Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent work has demonstrated that many bee species have specific cytochrome P450 enzymes (P450s) that can efficiently detoxify certain insecticides. The presence of these P450s, belonging or closely related to the CYP9Q subfamily (CYP9Q-related), is generally well conserved across the diversity of bees. However, the alfalfa leafcutter bee,
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Registered trials
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