Evidence map›Paper›PMID 38283228›Full record

ArticleRSC medicinal chemistry2024

NMR

Daniel Hymon, Jason Martins, Christian Richter, Sridhar Sreeramulu, Anna Wacker, Jan Ferner, Neeraj N Patwardhan, Amanda E Hargrove, Harald Schwalbe

Open access · hybridAbstract read
In one paragraph

Article in RSC medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. How does NMR support SARS-CoV-2 protein-ligand interaction studies?Analytical and bioanalytical chemistry · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Perspectives on Applications ofMolecules (Basel, Switzerland) · 2024
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Daniel HymonInstitute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe-University Frankfurt Max-von-Laue-Str. 7 60438 Frankfurt/Main Germany schwalbe@nmr.uni-frankfurt.de.
Jason MartinsInstitute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe-University Frankfurt Max-von-Laue-Str. 7 60438 Frankfurt/Main Germany schwalbe@nmr.uni-frankfurt.de.
Christian RichterInstitute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe-University Frankfurt Max-von-Laue-Str. 7 60438 Frankfurt/Main Germany schwalbe@nmr.uni-frankfurt.de.
Sridhar SreeramuluInstitute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe-University Frankfurt Max-von-Laue-Str. 7 60438 Frankfurt/Main Germany schwalbe@nmr.uni-frankfurt.de.
Anna WackerInstitute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe-University Frankfurt Max-von-Laue-Str. 7 60438 Frankfurt/Main Germany schwalbe@nmr.uni-frankfurt.de.
Jan FernerInstitute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe-University Frankfurt Max-von-Laue-Str. 7 60438 Frankfurt/Main Germany schwalbe@nmr.uni-frankfurt.de.
Neeraj N PatwardhanDepartment of Chemistry, Duke University Durham North Carolina 27708 USA.
Amanda E HargroveDepartment of Chemistry, Duke University Durham North Carolina 27708 USA.ORCID https://orcid.org/0000-0003-1536-6753
Harald SchwalbeInstitute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Goethe-University Frankfurt Max-von-Laue-Str. 7 60438 Frankfurt/Main Germany schwalbe@nmr.uni-frankfurt.de.ORCID https://orcid.org/0000-0001-5693-7909
Goethe University Frankfurt · DEDuke University · US

Funding

Center for Structural Biology of HIV RNAU54AI170660 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALICE TELESNITSKY · 2022 to 2026
$32.1M
Harnessing Small Molecules to Probe the Structure and Function of Regulatory RNAsR35GM124785 · NIGMS · DUKE UNIVERSITY · PI HARGROVE, AMANDA E · 2017 to 2023
$2.8M
NIAID NIH HHS U54 AI170660NIGMS NIH HHS R35 GM124785
6 · The paper itself

Abstract

Development of new antiviral medication against the beta-coronavirus SARS-CoV-2 (SCoV2) is actively being pursued. Both NMR spectroscopy and crystallography as structural screening technologies have been utilised to screen the viral proteome for binding to fragment libraries. Here, we report on NMR screening of elements of the viral RNA genome with two different ligand libraries using

Identifiers

PMID38283228
PMCPMC10809358
OpenAlexW4389104239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.