Evidence map›Paper›PMID 38283222›Full record

ArticleRSC medicinal chemistry2024

Novel indolyl 1,2,4-triazole derivatives as potential anti-proliferative agents:

Sarah A Ghobish, Khaled O Mohamed, Nahla Farag, Doaa B Farag

Open access · greenAbstract read
In one paragraph

Article in RSC medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sarah A GhobishPharmaceutical Chemistry Department, Faculty of Pharmacy, Misr International University Cairo Egypt nahla.farag@miuegypt.edu.eg doaa.boshra@miuegypt.edu.eg.ORCID https://orcid.org/0000-0001-5050-183X
Khaled O MohamedPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University Cairo Egypt.
Nahla FaragPharmaceutical Chemistry Department, Faculty of Pharmacy, Misr International University Cairo Egypt nahla.farag@miuegypt.edu.eg doaa.boshra@miuegypt.edu.eg.ORCID https://orcid.org/0000-0003-0978-7973
Doaa B FaragPharmaceutical Chemistry Department, Faculty of Pharmacy, Misr International University Cairo Egypt nahla.farag@miuegypt.edu.eg doaa.boshra@miuegypt.edu.eg.ORCID https://orcid.org/0000-0002-7541-1889
Misr International University · EGSinai University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new series of indolyl 1,2,4-triazole scaffolds was designed, synthesised, and biologically evaluated for their inhibitory activity against both CDK4 and CDK6. The results ranged from 0.049 μM to 3.031 μM on CDK4 and from 0.075 μM to 1.11 μM on CDK6 when compared to staurosporine, with IC

Identifiers

PMID38283222
PMCPMC10809324
OpenAlexW4388983425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.