Discovery of novel β-elemene hybrids with hydrogen sulfide-releasing moiety possessing cardiovascular protective activity for the treatment of atherosclerosis.
Wenjian Zhu, Hongyu Wu, Chen He, Huajian Zhu, Hong Yao, Yun Cao, Yueman Shi, Xiaotong Chen, Xue Feng, Shengtao Xu and 2 more
Article in RSC medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 3 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
12 authors at 3 institutions in 2 countries.
Wenjian ZhuState Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University 24 Tong Jia Xiang Nanjing 210009 PR China cpuxst@cpu.edu.cn jinyixu@china.com.
Hongyu WuState Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University 24 Tong Jia Xiang Nanjing 210009 PR China cpuxst@cpu.edu.cn jinyixu@china.com.
Chen HeState Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University 24 Tong Jia Xiang Nanjing 210009 PR China cpuxst@cpu.edu.cn jinyixu@china.com.
Huajian ZhuState Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University 24 Tong Jia Xiang Nanjing 210009 PR China cpuxst@cpu.edu.cn jinyixu@china.com.
Hong YaoState Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University 24 Tong Jia Xiang Nanjing 210009 PR China cpuxst@cpu.edu.cn jinyixu@china.com.
Yun CaoJinling High School Nanjing Jiangsu 210005 China.
Yueman Shi50 Dongbei Street Development Zone, CSPC Yuanda (Dalian) Pharmaceutical Co., Ltd Dalian Liaoning 116600 China.
Xiaotong Chen50 Dongbei Street Development Zone, CSPC Yuanda (Dalian) Pharmaceutical Co., Ltd Dalian Liaoning 116600 China.
Xue Feng50 Dongbei Street Development Zone, CSPC Yuanda (Dalian) Pharmaceutical Co., Ltd Dalian Liaoning 116600 China.
Shengtao XuState Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University 24 Tong Jia Xiang Nanjing 210009 PR China cpuxst@cpu.edu.cn jinyixu@china.com.
Zheying ZhuDivision of Molecular Therapeutics & Formulation, School of Pharmacy, The University of Nottingham, University Park Campus Nottingham NG7 2RD UK.
Jinyi XuState Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University 24 Tong Jia Xiang Nanjing 210009 PR China cpuxst@cpu.edu.cn jinyixu@china.com.ORCID https://orcid.org/0000-0002-1961-0402
China Pharmaceutical University · CNJinling Institute of Technology · CNUniversity of Nottingham · GB
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Herein, a series of novel β-elemene hybrids with different types of hydrogen sulfide (H
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Discovery of novel β-elemene hybrids with hydrogen sulfide-releasing moiety possessing cardiovascular protective activity for the treatment of atherosclerosis. · full record | OpenQuestion