Evidence map›Paper›PMID 38283198›Full record

ReviewInternational journal of nanomedicine2024

Bacteria-Based Nanoprobes for Cancer Therapy.

Yiping Lu, Nan Mei, Yinwei Ying, Dongdong Wang, Xuanxuan Li, Yajing Zhao, Yuqi Zhu, Shun Shen, Bo Yin

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Microbial medicines: Unlocking the therapeutic potential of the microbiome in cancer treatment.Journal of controlled release : official journal of the Controlled Release Society · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yiping Lu *Department of Radiology, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Nan Mei *Department of Radiology, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Yinwei Ying *Department of Radiology, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Dongdong WangDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Xuanxuan LiDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Yajing ZhaoDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Yuqi ZhuDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Shun ShenPharmacy Department, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, People's Republic of China.
Bo YinDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.ORCID 0000-0003-4134-8583
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surgical removal together with chemotherapy and radiotherapy has used to be the pillars of cancer treatment. Although these traditional methods are still considered as the first-line or standard treatments, non-operative situation, systemic toxicity or resistance severely weakened the therapeutic effect. More recently, synthetic biological nanocarriers elicited substantial interest and exhibited promising potential for combating cancer. In particular, bacteria and their derivatives are omnipotent to realize intrinsic tumor targeting and inhibit tumor growth with anti-cancer agents secreted and immune response. They are frequently employed in synergistic bacteria-mediated anticancer treatments to strengthen the effectiveness of anti-cancer treatment. In this review, we elaborate on the development, mechanism and advantage of bacterial therapy against cancer and then systematically introduce the bacteria-based nanoprobes against cancer and the recent achievements in synergistic treatment strategies and clinical trials. We also discuss the advantages as well as the limitations of these bacteria-based nanoprobes, especially the questions that hinder their application in human, exhibiting this novel anti-cancer endeavor comprehensively.

Indexed as

Antineoplastic AgentsNeoplasmsBacteriaHumansAntineoplastic Agentsbacteria-based nanoprobebacteria-mediated synergistic cancer therapyclinical trialnanomedicinetumor immune microenvironmenttumor targeting

Identifiers

PMID38283198
PMCPMC10821665
OpenAlexW4391141083

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.