ArticleMacromolecules2024
Effect of Polyelectrolyte Charge Density on the Linear Viscoelastic Behavior and Processing of Complex Coacervate Adhesives.
Article in Macromolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Biomimetic Coacervate Coatings: From Phase Separation Fundamentals to Advanced Biomedical Applications.Biomimetics (Basel, Switzerland) · 2026Review
- Stretchable Water-Free Liquid Crystalline Polyelectrolyte Complexes.ACS applied polymer materials · 2026Article
- Thermoresponsive Complex Coacervates as Advanced Carriers for Cell-Laden Liquid-Core Capsules for Biomedical Applications.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Effect of Copolymer Chemistry on the Humidity- and Temperature-Dependent Mechanical Properties and Structure of Polyelectrolyte Complexes.Macromolecules · 2026Article
- Developing Design Rules for Polyelectrolyte Complex Materials: Role of Polyelectrolyte Length, Charged Group, and Backbone.Macromolecules · 2026Article
- Construction of Peptide Amphiphile-Coated Coacervates with Selective Permeability.ACS biomaterials science & engineering · 2026Article
- Spider Silk Inspired Processing of Liquid Crystalline Complex Coacervates.ACS macro letters · 2026Article
- Complex coacervate tissue adhesives: effect of polycation chemistry and ionic strength on cytocompatibility.Journal of materials science. Materials in medicine · 2026Article
- Role of Charge Patterning and Hydrophobicity in Peptide-Based Complex Coacervates.Biomacromolecules · 2025Article
- Bioinspired Pressure Sensitive Adhesives Based on Natural Deep Eutectic Solvents.Macromolecules · 2025Article
- Polyelectrolyte Complex Coacervate Adhesive for Wearable Medical Devices.Macromolecular rapid communications · 2025Article
- 3D-Printable Granular Hydrogel Composed of Hyaluronic Acid-Chitosan Hybrid Polyelectrolyte Complex Microgels.Biomacromolecules · 2025Article
- Improving Complex Coacervate Tissue Adhesive Performance Using Bridging Polymer Chains.Biomacromolecules · 2025Article
- Brittle-to-Ductile Transitions of Polyelectrolyte Complexes: Humidity, Temperature, and Salt.Macromolecules · 2025Article
- Sticky Science: Using Complex Coacervate Adhesives for Biomedical Applications.Advanced healthcare materials · 2025Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is well-known that the phase behavior and physicochemical and adhesive properties of complex coacervates are readily tuneable with the salt concentration of the medium. For toxicity reasons, however, the maximum applicable salt concentration in biomedical applications is typically low. Consequently, other strategies must be implemented in order to optimize the properties of the resulting complex coacervates. In this work, the effect of the charge density of a strong polyanion on the properties of complex coacervates was studied. To control this charge density, statistical anionic/charge-neutral hydrophilic copolymers were synthesized by means of an elegant protection/deprotection strategy and subsequently complexed with a strong polycation. The resulting complexes were observed to have an increasing water content as well as faster relaxation dynamics, with either increasing salt concentration or decreasing charge density. Time-salt and time-salt-charge density superpositions could be performed and showed that the relaxation mechanism of the complex coacervates remained unchanged. When the charge density was decreased, lower salt concentration complexes became suitable for viscoelastic adhesion with improved injectability. Such complex coacervates are promising candidates for injectable biomedical adhesives.
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Registered trials
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