ArticleFrontiers in medicine2023
Higher levels of systemic immune-inflammatory index are associated with the prevalence of gallstones in people under 50 years of age in the United States: a cross-sectional analysis based on NHANES.
Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Article
- Laboratory and genetic characteristic associated with gallbladder-related outcomes in sickle cell disease in Brazil: results from the REDS-III multicenter cohort study.Annals of hematology · 2026Article
- Prognostic role of systemic inflammatory indices in predicting the severity of acute calculous cholecystitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- Association between cardiometabolic index and gallstones: a cross-sectional study based on NHANES 2017-2020.European journal of medical research · 2025Article
- The mediating role of inflammatory factors in the relationship between obesity and gallstone disease: evidence from the NHANES 2017-2020.European journal of medical research · 2025Article
- The Association Between Plant-Based Diet and Gallstone Disease: A Case-Control Study.Middle East journal of digestive diseases · 2025Article
- Positive association between cardiometabolic index and gallstones, with greater impact on women and those younger than 50 years: the NHANES 2017-2020 cross-sectional study.BMC public health · 2025Article
- Association between C-reactive protein to lymphocyte ratio and gallstones: a cross-sectional study.BMC gastroenterology · 2025Article
- The association between inflammatory biomarkers and gallstones in Americans under 50 years old.BMC gastroenterology · 2025Article
- MAFLD mediates the association between CHR and gallstones in the U.S. adults: evidence from NHANES 2021-2023.BMC gastroenterology · 2025Article
- Inflammatory burden index (IBI) and body roundness index (BRI) in gallstone risk prediction: insights from NHANES 2017-2020.Lipids in health and disease · 2025Article
- The association between life's essential 8 and gallstones: A cross-sectional study.Scientific reports · 2025Article
- Association between advanced lung cancer inflammation index and gallstone prevalence among U.S. adults: A population-based study.PloS one · 2025Article
- Association between Neutrophil-to-high-density lipoprotein-cholesterol ratio and gallstones: insights from the national health and nutrition examination survey (2017-2020).Lipids in health and disease · 2024Article
- Association of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and gallstones among US adults aged ≤ 50 years: a cross-sectional study from NHANES 2017-2020.Lipids in health and disease · 2024Article
- Association between dietary magnesium intake and gallstones: the mediating role of atherogenic index of plasma.Lipids in health and disease · 2024Article
- Characterizing the relationships between dietary indices, gallstone prevalence and the need for gallbladder surgery in the general US population.Frontiers in nutrition · 2024Article
- Positive association between advanced lung cancer inflammation index and gallstones, with greater impact on women: a cross-sectional study of the NHANES database.Frontiers in nutrition · 2024Article
- Microbial characteristics of bile in gallstone patients: a comprehensive analysis of 9,939 cases.Frontiers in microbiology · 2024Article
- Non-linear relationship between the first meal time of the day and gallstone incidence in American adults: a population-based cross-sectional study.Frontiers in nutrition · 2024Article
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Abstract
Introduction: Inflammation plays a significant role in gallstones formation. The prognosis of various illnesses was initially predicted using the systemic immune-inflammatory index (SII). We performed an updated analysis on the impact of SII and gallstones. Methods: To investigate the connection between the SII and gallstones occurrence in a sample of individuals from the National Health and Nutrition Examination Survey (NHANES) database from 2017 to 2020, we employed logistic regression analysis, subgroup analysis, and smoothing curve fitting. Results: In our study, an aggregate of 4,950 individuals over the age of 20 were enrolled, and 429 of them claimed to have gallstones. A fully adjusted model showed that the third and fourth quartiles of SII was parallel associated with gallstones in adults (OR = 2.43, 95% CI = 1.39-4.26; OR = 2.97, 95% CI = 1.72-5.16) under 50 years. Subgroup analysis and smoothed curve fitting provided evidence in favor of this finding. Conclusion: According to our research, gallstones are more likely to occur in US adults younger than 50 years.
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