Evidence map›Paper›PMID 38283036›Full record

ArticleArabian journal of chemistry2024

Structure-based design, and development of amidinyl, amidoximyl and hydroxamic acid based organic molecules as novel antimalarial drug candidates.

Glory P Adebayo, Gbolahan O Oduselu, Damilola V Aderohunmu, Karel D Klika, Grace I Olasehinde, Olayinka O Ajani, Ezekiel Adebiyi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Arabian journal of chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Glory P AdebayoCovenant University Bioinformatics Research (CUBRe), Covenant University, Ota, Nigeria.
Gbolahan O OduseluCovenant University Bioinformatics Research (CUBRe), Covenant University, Ota, Nigeria.
Damilola V AderohunmuCovenant University Bioinformatics Research (CUBRe), Covenant University, Ota, Nigeria.
Karel D KlikaNMR Structural Analysis, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Grace I OlasehindeCovenant University Bioinformatics Research (CUBRe), Covenant University, Ota, Nigeria.
Olayinka O AjaniCovenant University Bioinformatics Research (CUBRe), Covenant University, Ota, Nigeria.
Ezekiel AdebiyiCovenant University Bioinformatics Research (CUBRe), Covenant University, Ota, Nigeria.
Covenant University · NGGerman Cancer Research Center · DE

Funding

H3ABioNet: informatics solutions for H3AfricaU24HG006941 · NHGRI · UNIVERSITY OF CAPE TOWN · PI MULDER, NICOLA · 2017 to 2021
$12.9M
WEST AFRICAN SUSTAINABLE LEADERSHIP AND INNOVATION TRAINING IN BIOINFORMATICS RESEARCH (WASLITBRe)U2RTW010679 · FIC · COVENANT UNIVERSITY · PI ADEBIYI, EZEKIEL FEMI, AMOAKO-YIRENKYI, PETER · 2017 to 2021
$1.4M
FIC NIH HHS U2R TW010679NHGRI NIH HHS U24 HG006941
6 · The paper itself

Abstract

Malaria remains a significant global health concern causing numerous fatalities and the emergence of antimalarial drug resistance highlights the urgent need for novel therapeutic options with innovative mechanisms of action and targets. This study aimed to design potential inhibitors of

Indexed as

Acute toxicityCytotoxicityHydroxamic acidsMalariaSuppression

Identifiers

PMID38283036
PMCPMC10810238
OpenAlexW4389917902

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.