Evidence map›Paper›PMID 38282747›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2023

A European Multi-Center Analysis of Extracorporeal Photopheresis as Therapy for Chronic Lung Allograft Dysfunction.

Alberto Benazzo, Cecilia Bagnera, Fabio Ius, Claudia Del Fante, Jens Gottlieb, Konrad Hoetzenecker, Federica Meloni, Peter Jaksch, Mark Greer

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. European society for organ transplantation clinical practice guideline on prevention and treatment of chronic lung allograft dysfunction.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Guideline
  2. Trial
  3. Article
  4. Review
  5. The Top 12 Most Impactful Papers in Clinical Transplantation in 2025: TI Editors' Choice.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Current Usage of Extracorporeal Photopheresis in Solid Organ Transplantations in Europe: A Narrative Review.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Alberto BenazzoDepartment of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.
Cecilia BagneraMalattie dell'Apparato Respiratorio, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Fabio IusDepartment of Respiratory Medicine, Hannover Medical School, Hannover, Germany.
Claudia Del FanteServizio Immunoematologia e Medicina Trasfusionale, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Jens GottliebDepartment of Respiratory Medicine, Hannover Medical School, Hannover, Germany.
Konrad HoetzeneckerDepartment of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.
Federica MeloniMalattie dell'Apparato Respiratorio, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Peter JakschDepartment of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.
Mark GreerDepartment of Respiratory Medicine, Hannover Medical School, Hannover, Germany.
Medical University of Vienna · ATPoliclinico San Matteo Fondazione · ITGerman Center for Lung Research · DEMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracorporeal photopheresis (ECP) is used by few lung transplant centers to treat chronic lung allograft dysfunction (CLAD). Although reported results suggest a beneficial effect on CLAD progression, evidence is limited to single center experiences. The aim of this study is to analyze outcomes of ECP in a large multicenter European cohort. The primary endpoint was patient survival after initiation of ECP. This study included 631 patients, 87% suffered from bronchiolitis obliterans syndrome (BOS), and 13% had restrictive allograft syndrome (RAS). Long-term stabilization was achieved in 42%, improvement in 9%, and no response in 26%. Within the first 12 months of therapy, 23% of patients died. Patients' survival after initiation of ECP at 5 years was 56% in stable, 70% in responders, and 35% in non-responders (

Indexed as

AllograftsLung TransplantationPhotopheresisCohort StudiesHumansCLADextracorporeal photopheresisFEV1lung functionlung transplantation

Identifiers

PMID38282747
PMCPMC10811603
OpenAlexW4390789312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.