Evidence map›Paper›PMID 38282503›Full record

Trial reportAnaesthesiology intensive therapy2023

Analgesic efficacy of two different volumes of local anaesthetics in ultrasound-guided modified approach to the thoracolumbar interfascial plane block in patients undergoing lumbar spine surgeries: a randomized controlled trial.

Bassant Abdelhamid, Eslam Ayman, Tareq Nabil, Waleed Ibrahim Hamimy, Mohamed Abd El-Monem Morsy

Registry-linked trialOpen access · diamondAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Anaesthesiology intensive therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05276908 (Analgesic Efficacy of Two Different Volumes of Local Anesthetics in Ultrasound-guided Modified Approach of Thoracolumbar Block in Patients Undergoing Lumbar Spine Surgeries; a Randomized Controlled Trial.), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05276908 nacompletednot on this map

Analgesic Efficacy of Two Different Volumes of Local Anesthetics in Ultrasound-guided Modified Approach of Thoracolumbar Block in Patients Undergoing Lumbar Spine Surgeries; a Randomized Controlled Trial.

TypeinterventionalSponsorCairo UniversityRan2022 to 2022Enrolled80ConditionsPostoperative PainArmsThoracolumbar interfascial plane block (TLIP)Technique, Anesthetic Management, Bupivacaine Injection 10ml, Bupivacaine Injection 20ml
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Bassant AbdelhamidDepartment of Anesthesia, Surgical ICU and Pain Management, Kasr-Alainy Faculty of Medicine, Cairo University, Egypt.
Eslam AymanDepartment of Anesthesia, Surgical ICU and Pain Management, Kasr-Alainy Faculty of Medicine, Cairo University, Egypt.
Tareq NabilDepartment of Anesthesia, Surgical ICU and Pain Management, Kasr-Alainy Faculty of Medicine, Cairo University, Egypt.
Waleed Ibrahim HamimyDepartment of Anesthesia, Surgical ICU and Pain Management, Kasr-Alainy Faculty of Medicine, Cairo University, Egypt.
Mohamed Abd El-Monem MorsyDepartment of Anesthesia, Surgical ICU and Pain Management, Kasr-Alainy Faculty of Medicine, Cairo University, Egypt.
Cairo University · EGArmed Forces College of Medicine · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere is a lack of clarity regarding the ideal local anaesthetic volume for modified thoracolumbar interfascial plane (mTLIP) block. This study was designed to investigate the analgesic efficacy of two different volumes of bupivacaine 0.25% (20 mL, and 10 mL) for ultrasound-guided mTLIP block in patients undergoing lumbar spine surgeries. MATERIAL AND

methodsA total of 80 patients received single shot of bilateral mTLIP block at the mid- level of the operative intervention and were randomly allocated into one of the two groups to receive either 10 or 20 mL 0.25% bupivacaine on each side. Total morphine consumption in the first 24 hours postoperative was set as the primary outcome. Time to first rescue analgesia and Numeric Rating Scale (NRS) were set as secondary outcomes.

resultsThere was no significant difference in the primary outcome: 6.20 ± 2.18 mg (10 mL Group) vs. 5 ± 0.00 mg (20 mL Group), P = 0.056. The time of first request of rescue morphine was significantly shorter in 10 mL Group (7.80 ± 3.98 hours) as compared to the 20 mL Group (13.23 ± 3.00 hours), P < 0.001. NRS at rest and movement in all time measurements was significantly higher in 10 mL Group.

conclusionsBilateral mTLIP block using 40 mL of 0.25% bupivacaine (20 mL on each side) increased the postoperative total analgesic duration for lumbar spine surgeries, and was associated with a lower postoperative pain scores compared to 20 mL of 0.25% bupivacaine (10 mL on each side). CLINICAL TRIAL REGISTRATION ID: The study was registered at clinicaltrials.gov (ID: NCT05276908) before patient's enrolment.

Indexed as

Anesthetics, LocalNerve BlockAnalgesicsAnalgesics, OpioidBupivacaineHumansMorphinePostoperative PainUltrasonography, InterventionalAnalgesicsAnalgesics, OpioidAnesthetics, LocalBupivacaineMorphinedifferent volumes of local anestheticslumbar spine surgeriesmodified thoracolumbar interfascial plane block

Identifiers

PMID38282503
PMCPMC10801459
OpenAlexW4391319402

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.