Evidence map›Paper›PMID 38282410›Full record

ArticleJournal of microbiology and biotechnology2024

Steamed Ginseng Berry Powder Ameliorates Skeletal Muscle Atrophy via Myogenic Effects.

Jungbum Kim, Hui-Ji Choi, Donghyuk Seo, Sang-Ah Lee, Jong Beom Heo, Dong Hyuk Baek, Wonhwa Lee, Gyu Yong Song

Open access · bronzeAbstract read
In one paragraph

Article in Journal of microbiology and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jungbum KimDepartment of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Hui-Ji ChoiCollege of Pharmacy, Chungnam National University, Daejeon 34134, Republic of Korea.
Donghyuk SeoDepartment of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Sang-Ah LeeFaculty of Biotechnology, College of Applied Life Sciences, Jeju national University, Jeju 63243, Republic of Korea.
Jong Beom HeoCollege of Pharmacy, Chungnam National University, Daejeon 34134, Republic of Korea.
Dong Hyuk BaekCollege of Pharmacy, Chungnam National University, Daejeon 34134, Republic of Korea.
Wonhwa LeeDepartment of Chemistry, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Gyu Yong SongCollege of Pharmacy, Chungnam National University, Daejeon 34134, Republic of Korea.
Chungnam National University · KRSungkyunkwan University · KRKorea Institute of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcopenia is an age-related loss of muscle mass and function for which there is no approved pharmacological treatment. We tested direct efficacy by evaluating grip strength improvement in a sarcopenia mouse model rather than drug screening, which inhibits specific molecular mechanisms. Various physiological functions of ginseng berries are beneficial to the human body. The present study aimed to evaluate the efficacy and safety of steamed ginseng berry powder (SGBP). SGBP administration increased myotube diameter and suppressed the mRNA expression of sarcopenia-inducing molecules. SGBP also reduced the levels of inflammatory transcription factors and cytokines that are known to induce sarcopenia. Oral administration of SGBP improved muscle mass and physical performance in a mouse model of sarcopenia. In summary, our data suggest that SGBP is a novel therapeutic candidate for the amelioration of muscle weakness, including sarcopenia.

Indexed as

PanaxSarcopeniaAnimalsFruitHumansMiceMuscle Fibers, SkeletalMuscle, SkeletalMuscular AtrophyPowdersPowdersmyogenesisSarcopeniaskeletal muscle atrophysteamed ginseng berry powder

Identifiers

PMID38282410
PMCPMC10840479
OpenAlexW4391319764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.