ArticleBrain and behavior2024
Shared genetic risk between anorexia nervosa and cardiovascular disease events: Evidence from genome-wide association studies.
Article in Brain and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Eating disorders, nutrient intake, and cardiometabolic risks: a cross-sectional study in Turkish adults.BMC public health · 2025Article
- Shared genetics and causal relationship between sociability and the brain's default mode network.Psychological medicine · 2025Article
- Incidence and Risk of Cardiovascular Outcomes in Patients With Anorexia Nervosa.JAMA network open · 2024Article
- Shared genetic risk between anorexia nervosa and cardiovascular disease events: Evidence from genome-wide association studies.Brain and behavior · 2024Article
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Authors and funding
6 authors.
Funding
Abstract
objectiveCardiovascular complications occur in up to 80% of patients with anorexia nervosa (AN), yet the underlying mechanisms warrant further investigation. We assessed the genetic correlation (r
methodWe used genome-wide association study summary statistics for AN (N = 72,517), AN with binge eating (N = 12,630), AN without binge eating (N = 12,516), and six CVD events (N = 390,142 to 977,323). We calculated the r
resultsSignificant r DISCUSSION: Some loci affect the liability to AN and CVD in opposite directions and the shared genetic effects may not be consistent across all CVD events. Our results provide further evidence suggesting that the elevated cardiovascular risk in AN may not be due to shared genetic underpinnings, but more likely a downstream consequence of the disease.
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