Evidence map›Paper›PMID 38281864›Full record

ArticleTrends in microbiology2024

Starvation helps transition to abundance - a ferrosome story.

Subham Mridha, Michael C Abt

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Trends in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Dietary iron attenuatesVirulence · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Subham MridhaDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Michael C AbtDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: michael.abt@pennmedicine.upenn.edu.

Funding

Project 3: Defining adaptive immune interactions that shape Clostridioides difficile infectionU19AI174998 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Frederic D Bushman, DREW WEISSMAN · 2023 to 2026
$7.6M
Investigating Immune-Microbiome interactions during treatment of Clostridioides difficile with fecal microbiome transplantationR01AI158830 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ABT, MICHAEL C. · 2021 to 2025
$2.4M
NIAID NIH HHS R01 AI158830NIAID NIH HHS U19 AI174998
6 · The paper itself

Abstract

Iron is an essential nutrient for bacterial pathogenesis. In their study, Skaar and colleagues (Pi et al.) discovered and determined the detailed structure of ferrosomes within Clostridioides difficile, the iron-storage organelles that form under iron-limited conditions in anticipation of future iron overload.

Indexed as

Bacterial ProteinsFerric CompoundsIronGene Expression Regulation, BacterialBacterial ProteinsFerric CompoundsferrosomeIronClostridioides difficileelectron microscopyenergy dispersive X-ray spectroscopyferric uptake regulator (Fur)ferrosomeiron homeostasisnutritional immunity

Identifiers

PMID38281864
PMCPMC10967234

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.