ArticleJournal of epidemiology2024
Nonrestorative Sleep and Type 2 Diabetes Incidence: The Aichi Workers' Cohort Study.
Article in Journal of epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Nonrestorative Sleep and Poor Self-Reported Physical and Mental Health among Middle-Aged Japanese Adults: A Cross-Sectional Study.JMA journal · 2026Article
- Changes in body mass index and waist circumference as predictors of incident prediabetes: the Aichi Workers' Cohort Study.Scientific reports · 2026Article
- Association between tendency to overeat and the incidence of prediabetes: Aichi Workers' Cohort Study.Environmental health and preventive medicine · 2026Article
- Nonrestorative sleep is associated with somatic and depressive symptoms in Japanese junior high school students.Journal of physiological anthropology · 2025Article
- Association between eveningness and depressive symptoms in daytime workers: A cross-sectional analysis of the Aichi Workers' Cohort Study.Fujita medical journal · 2025Article
- Prevalence of nonrestorative sleep before and during the COVID-19 pandemic: based on a nationwide cross-sectional survey among Japanese in 2019 and 2022.Environmental health and preventive medicine · 2025Article
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Authors and funding
11 authors.
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Abstract
backgroundThe term "nonrestorative sleep (NRS)" refers to an unrefreshed feeling at wake-up and is a domain of poor sleep quality. Previous research has demonstrated that NRS is linked to a number of diseases and adverse health outcomes, but less is known regarding the link between NRS and diabetes, particularly in Japanese.
methodsWe studied 3,665 middle-aged male participants of the Aichi Workers' Cohort Study who were followed-up from 2002 through 2019. Cox proportional hazards models estimated hazard ratios (HRs) and 95% confidence intervals (CIs) of incident type 2 diabetes mellitus (T2DM) in relation to NRS adjusted for potential confounding variables.
resultsDuring a median follow-up of 14.6 years, 421 type 2 diabetes cases were identified. Participants with NRS had a higher crude incidence rate of T2DM (11.2/1,000 person-years), compared to participants without NRS (9.3/1,000 person-years). In the fully adjusted model, individuals who reported having NRS had a significantly higher risk of developing T2DM (HR1.36; 95% CI, 1.10-1.67). The association was observed only in participants under 50 years old (HR 1.82; 95% CI, 1.36-2.43), not in the older (50 years or older) participants (P for interaction = 0.025). In contrast, stratified analyses by the presence of shift work, obesity, or sleep duration showed similar associations in all the strata.
conclusionNRS was associated with higher risk of T2DM in middle-aged Japanese male workers independent of a variety of lifestyle factors and other sleep problems.
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