Evidence map›Paper›PMID 38281325›Full record

ArticleESMO open2024

Sexual quality of life of adolescents and young adult breast cancer survivors.

N J M C Vrancken Peeters, C Vlooswijk, R M Bijlsma, S E J Kaal, J M Kerst, J M Tromp, M E M M Bos, T van der Hulle, R I Lalisang, J Nuver and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in ESMO open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07658937 (Improving Sexual and Reproductive Health Communication Between Adolescent and Young Adult Oncology Patients and Clinicians), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
15.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07658937 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Improving Sexual and Reproductive Health Communication Between Adolescent and Young Adult Oncology Patients and Clinicians: ReSPECT Intervention Proof-of-Concept Testing

TypeinterventionalSponsorConnecticut Children's Medical CenterRan2026 to 2029Enrolled30ConditionsHealth-Related Quality-of-Life, Cancer, Health CommunicationArmsReSPECT
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Preliminary evaluation of the acceptability, appropriateness, and feasibility of an online sexual health educational video series for breast cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Trial
  3. Article
  4. Review
  5. Reproductive concerns and quality of life among Chinese women undergoing fertility-sparing surgery for gynecologic malignancies: a mixed-methods study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  6. Article
  7. Article
  8. Quality of life in very long-term (including > 20 years' follow-up) early-stage breast cancer survivors from Spain.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  9. Long-term health-related quality of life among adolescent and young adult breast cancer survivors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 1 country.

N J M C Vrancken PeetersDepartment of Medical Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam; Department of Plastic and Reconstructive Surgery, Erasmus MC Cancer Institute, Erasmus University Medical Centre, Rotterdam.
C VlooswijkResearch and Development, Netherlands Comprehensive Cancer Organisation, Utrecht.
R M BijlsmaDepartment of Medical Oncology, University Medical Centre, Utrecht.
S E J KaalDepartment of Medical Oncology, Radboud University Medical Centre, Nijmegen.
J M KerstDepartment of Medical Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam.
J M TrompDepartment of Medical Oncology, Amsterdam University Medical Centres, Amsterdam.
M E M M BosDepartment of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Centre, Rotterdam.
T van der HulleDepartment of Medical Oncology, Leiden University Medical Centre, Leiden.
R I LalisangDepartment of Internal Medicine, Division of Medical Oncology, GROW-School of Oncology and Reproduction, Maastricht UMC+ Comprehensive Cancer Centre, Maastricht.
J NuverDepartment of Medical Oncology, University Medical Centre Groningen, Groningen.
M C M KouwenhovenDepartment of Neurology, Amsterdam UMC, Amsterdam University Medical Centres, Amsterdam.
I M C van der PloegDepartment of Surgical Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam.
W T A van der GraafDepartment of Medical Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Centre, Rotterdam.
O HussonDepartment of Medical Oncology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam; Department of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Amsterdam; Department of Surgical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Centre, Rotterdam, The Netherlands. Electronic address: o.husson@nki.nl.
The Netherlands Cancer Institute · NLAmsterdam University Medical Centers · NLErasmus MC Cancer Institute · NLLeiden University Medical Center · NLMaastricht University Medical Centre · NLNetherlands Comprehensive Cancer Organisation · NLRadboud University Nijmegen · NLUniversity Medical Center Groningen · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith increasing survival rates of adolescents and young adults (AYAs) with breast cancer, health-related quality of life (HRQoL) becomes more important. An important aspect of HRQoL is sexual QoL. This study examined long-term sexual QoL of AYA breast cancer survivors, compared sexual QoL scores with that of other AYA cancer survivors, and identified factors associated with long-term sexual QoL of AYA breast cancer survivors. MATERIALS AND

methodsData of the SURVAYA study were utilized for secondary analyses. Sexual QoL was assessed using the European Organization for Research and Treatment of Cancer Quality of Life cancer survivorship core questionnaire (EORTC QLQ-SURV100). Descriptive statistics were used to describe sexual QoL of AYA cancer survivors. Linear regression models were constructed to examine the effect of cancer type on sexual QoL and to identify factors associated with sexual QoL.

resultsOf the 4010 AYA cancer survivors, 944 had breast cancer. Mean sexual QoL scores of AYA breast cancer survivors ranged from 34.5 to 60.0 for functional domains and from 25.2 to 41.5 for symptom-orientated domains. AYA breast cancer survivors reported significantly lower sexual QoL compared to AYA survivors of other cancer types on all domains. Age, time since diagnosis, relationship status, educational level, chemotherapy, hormonal therapy, breast surgery, body image, and coping were associated with sexual QoL of AYA breast cancer survivors.

conclusionsAYA breast cancer survivors experience decreased sexual QoL in the long term (5-20 years) after diagnosis and worse score compared to AYA survivors of other cancer types, indicating a clear need to invest in supportive care interventions for those at risk, to enhance sexual well-being.

Indexed as

Breast NeoplasmsCancer SurvivorsAdolescentBreastFemaleHumansQuality of LifeSurvivorsYoung Adultadolescents and young adults (AYAs)breast cancerhealth-related quality of life (HRQoL)sexual quality of life (QoL)survivorship

Identifiers

PMID38281325
PMCPMC10937205
OpenAlexW4391279093

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.