ArticleAging clinical and experimental research2024
Association between low values of mean arterial pressure and impaired cognitive performance in older patients with mild cognitive impairment: cross-sectional preliminary findings from the STRENGTH Project.
Article in Aging clinical and experimental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Article
- Development of a clinical nomogram to assess the risk of cognitive impairment in community-dwelling middle-aged and older adults.BMC neurology · 2026Article
- Associations Between Cerebral Perfusion Pressure, Hemodynamic Parameters, and Cognitive Test Values in Normal-Tension Glaucoma Patients, Alzheimer's Disease Patients, and Healthy Controls.Medicina (Kaunas, Lithuania) · 2025Article
- The impact of arteriolosclerosis on cognitive impairment in decedents without severe dementia from the National Alzheimer's Coordinating Center.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Association between blood pressure and dementia in older adults: a cross-sectional study from China.Frontiers in aging neuroscience · 2024Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundUncontrolled blood pressure (BP) is a risk factor for Mild Cognitive Impairment (MCI) and dementia.
aimsThis study examined the relationship between BP and clinical/cognitive/neuropsychological aspects in MCI individuals.
methodsMCI patients underwent clinical, functional, cognitive and metacognitive, as well as psychological assessments. Social network, lifestyle characteristics, and medication prescriptions were also evaluated. Each patient underwent BP measurements.
resultsLower values of systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP) were associated with poorer cognitive performance. Notably, MAP showed greater capability in detecting impairments in attention and visuospatial abilities compared to SBP and DBP. DISCUSSION: These findings support the notion that in older individuals with MCI excessively low BP values, particularly MAP, might represent a risk and suggest that cerebral hypoperfusion may play a key role.
conclusionsRoutine assessment of MAP could aid clinicians in adjusting antihypertensive treatment and closely monitoring cognitive function in MCI patients.
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