Evidence map›Paper›PMID 38281071›Full record

ReviewRheumatology (Oxford, England)2024

A path to Glucocorticoid Stewardship: a critical review of clinical recommendations for the treatment of systemic lupus erythematosus.

George Bertsias, Anca Askanase, Andrea Doria, Amit Saxena, Edward M Vital

Abstract readReview
In one paragraph

Review in Rheumatology (Oxford, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

George BertsiasRheumatology and Clinical Immunology, University of Crete Medical School, Heraklion, Greece.ORCID 0000-0001-5299-1406
Anca AskanaseDivision of Rheumatology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0003-4597-5023
Andrea DoriaDivision of Rheumatology, Department of Medicine, University of Padova, Padova, Italy.ORCID 0000-0003-0548-4983
Amit SaxenaDivision of Rheumatology, Department of Medicine, NYU Langone Health, New York, NY, USA.ORCID 0000-0003-0098-1083
Edward M VitalLeeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.ORCID 0000-0003-1637-4755

Funding

AstraZeneca
6 · The paper itself

Abstract

Glucocorticoids (GCs) have revolutionized the management of SLE, providing patients with rapid symptomatic relief and preventing flares when maintained at low dosages. However, there are increasing concerns over GC-associated adverse effects and organ damage, which decrease patients' quality of life (QOL) and increase healthcare costs. This highlights the need to balance effective GC use and minimize toxicity in patients with SLE. Herein, we provide an overview of the theoretical considerations and clinical evidence, in addition to the variations and similarities across nine national and eight international recommendations regarding the use of GCs across SLE manifestations and how these compare with real-world usage. In line with this, we propose possible actions toward the goal of GC Stewardship to improve the QOL for patients with lupus while managing the disease burden.

Indexed as

GlucocorticoidsLupus Erythematosus, SystemicQuality of LifeHumansPractice Guidelines as TopicGlucocorticoidsglucocorticoidslupus erythematosuslupus nephritissystemic

Identifiers

PMID38281071
PMCPMC11215984

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.