Evidence map›Paper›PMID 38281052›Full record

Observational studyBMC public health2024

Ten-year trends of antibiotic prescribing in surgery departments of two private sector hospitals in Central India: a prospective observational study.

Kristina Skender, Anna Machowska, Shyam Kumar Dhakaita, Cecilia Stålsby Lundborg, Megha Sharma

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Kristina SkenderDepartment of Global Public Health, Health Systems and Policy, Karolinska Institutet, 17177, Stockholm, Sweden.
Anna MachowskaDepartment of Global Public Health, Health Systems and Policy, Karolinska Institutet, 17177, Stockholm, Sweden.
Shyam Kumar DhakaitaDepartment of Surgery, Ruxmaniben Deepchand Gardi Medical College, Surasa, Ujjain, 456006, India.
Cecilia Stålsby LundborgDepartment of Global Public Health, Health Systems and Policy, Karolinska Institutet, 17177, Stockholm, Sweden.
Megha SharmaDepartment of Global Public Health, Health Systems and Policy, Karolinska Institutet, 17177, Stockholm, Sweden. megha.sharma@ki.se.
Karolinska Institutet · SERuxmaniben Deepchand Gardi Medical College · IN

Funding

Asia link 348-2006-6633Vetenskapsrådet K2010-396- 70X-20514-04-3
6 · The paper itself

Abstract

backgroundInappropriate antibiotic use contributes to the global rise of antibiotic resistance, prominently in low- and middle-income countries, including India. Despite the considerable risk of surgical site infections, there is a lack of antibiotic prescribing guidelines and long-term studies about antibiotic prescribing in surgery departments in India. Therefore, this study aimed to analyse 10 years' antibiotic prescribing trends at surgery departments in two tertiary-care hospitals in Central India.

methodsData was prospectively collected from 2008 to 2017 for surgery inpatients in the teaching (TH-15,016) and the non-teaching hospital (NTH-14,499). Antibiotics were classified based on the World Health Organization (WHO) Access Watch Reserve system and analysed against the diagnoses and adherence to the National List of Essential Medicines India (NLEMI) and the WHO Model List of Essential Medicines (WHOMLEM). Total antibiotic use was calculated by DDD/1000 patient days. Time trends of antibiotic prescribing were analysed by polynomial and linear regressions.

resultsThe most common indications for surgery were inguinal hernia (TH-12%) and calculus of the kidney and ureter (NTH-13%). The most prescribed antibiotics were fluoroquinolones (TH-20%) and 3

conclusionTotal antibiotic use decreased in the last three (NTH) and five years (TH), whereas consumption of Watch antibiotics increased over 10 years in both hospitals. The choice of perioperative antibiotic prophylaxis was often inappropriate and antibiotic prescribing was mostly empirical. The results of this study confirmed the need for antibiotic prescribing guidelines and implementation of antimicrobial stewardship programs.

Indexed as

Anti-Bacterial AgentsPrivate SectorAntibiotic ProphylaxisHospitals, PrivateHumansIndiaAnti-Bacterial AgentsAntibiotic prescribing trendsAntimicrobial resistanceAWaReEssential medicines listIndiaNon-teaching hospitalPrivate sector hospitalsProphylactic antibioticSurgeryTeaching hospital

Identifiers

PMID38281052
PMCPMC10821557
OpenAlexW4391281769

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.