Evidence map›Paper›PMID 38280946›Full record

ReviewNPJ precision oncology2024

Diagnostic performance of deep learning in ultrasound diagnosis of breast cancer: a systematic review.

Qing Dan, Ziting Xu, Hannah Burrows, Jennifer Bissram, Jeffrey S A Stringer, Yingjia Li

Abstract readReview
In one paragraph

Review in NPJ precision oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  15. Breast Cancer Detection on Dual-View Sonography via Data-Centric Deep Learning.IEEE open journal of engineering in medicine and biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qing Dan *Department of Ultrasound, Nanfang Hospital, Southern Medical University, 510515, Guangzhou, China.
Ziting Xu *Department of Ultrasound, Nanfang Hospital, Southern Medical University, 510515, Guangzhou, China.
Hannah BurrowsHealth Sciences Library, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Jennifer BissramHealth Sciences Library, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
Jeffrey S A StringerGlobal Women's Health, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA. jeffrey_stringer@med.unc.edu.ORCID http://orcid.org/0000-0002-9590-7216
Yingjia LiDepartment of Ultrasound, Nanfang Hospital, Southern Medical University, 510515, Guangzhou, China. lyjia@smu.edu.cn.ORCID http://orcid.org/0000-0002-8885-2317

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep learning (DL) has been widely investigated in breast ultrasound (US) for distinguishing between benign and malignant breast masses. This systematic review of test diagnosis aims to examine the accuracy of DL, compared to human readers, for the diagnosis of breast cancer in the US under clinical settings. Our literature search included records from databases including PubMed, Embase, Scopus, and Cochrane Library. Test accuracy outcomes were synthesized to compare the diagnostic performance of DL and human readers as well as to evaluate the assistive role of DL to human readers. A total of 16 studies involving 9238 female participants were included. There were no prospective studies comparing the test accuracy of DL versus human readers in clinical workflows. Diagnostic test results varied across the included studies. In 14 studies employing standalone DL systems, DL showed significantly lower sensitivities in 5 studies with comparable specificities and outperformed human readers at higher specificities in another 4 studies; in the remaining studies, DL models and human readers showed equivalent test outcomes. In 12 studies that assessed assistive DL systems, no studies proved the assistive role of DL in the overall diagnostic performance of human readers. Current evidence is insufficient to conclude that DL outperforms human readers or enhances the accuracy of diagnostic breast US in a clinical setting. Standardization of study methodologies is required to improve the reproducibility and generalizability of DL research, which will aid in clinical translation and application.

Identifiers

PMID38280946
PMCPMC10821881

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.