ArticleJournal of experimental botany2024
ABA INSENSITIVE 2 promotes flowering by inhibiting OST1/ABI5-dependent FLOWERING LOCUS C transcription in Arabidopsis.
Article in Journal of experimental botany, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Uncovering the role of ABI2 as a key regulator of flowering time in Arabidopsis.Plant signaling & behavior · 2026Article
- Mitochondrial gene orf224 triggers retrograde signaling and reprogramming of anther cell fate in Brassica napus Polima CMS.The New phytologist · 2026Article
- A phosphatidic acid-based retrograde signaling pathway responsive to abiotic stress in Arabidopsis.The Plant journal : for cell and molecular biology · 2026Article
- Molecular Crosstalk Between Flowering Time and Drought Adaptation in Cereal Crops.Plants (Basel, Switzerland) · 2026Review
- Early Plant Development as a Systems-Level Trait: Integrating Omics, Artificial Intelligence, and Emerging Biotechnologies.Plants (Basel, Switzerland) · 2026Review
- Beyond dormancy: organ-specific gene regulatory networks control winter development in peach buds.Horticulture research · 2026Article
- Identification of CsAFP3-like as a novel gene regulating determinate growth of lateral branch in cucumber.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Comprehensive Analysis ofBiology · 2025Article
- Precision tuning of ABA signaling by ubiquitination of ABA receptors: modulating protein activity and localization.Journal of experimental botany · 2025Article
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Authors and funding
11 authors at 4 institutions in 3 countries.
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Abstract
The plant hormone abscisic acid (ABA) is an important regulator of plant growth and development and plays a crucial role in both biotic and abiotic stress responses. ABA modulates flowering time, but the precise molecular mechanism remains poorly understood. Here we report that ABA INSENSITIVE 2 (ABI2) is the only phosphatase from the ABA-signaling core that positively regulates the transition to flowering in Arabidopsis. Loss-of-function abi2-2 mutant shows significantly delayed flowering both under long day and short day conditions. Expression of floral repressor genes such as FLOWERING LOCUS C (FLC) and CYCLING DOF FACTOR 1 (CDF1) was significantly up-regulated in abi2-2 plants while expression of the flowering promoting genes FLOWERING LOCUS T (FT) and SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (SOC1) was down-regulated. Through genetic interactions we further found that ost1-3 and abi5-1 mutations are epistatic to abi2-2, as both of them individually rescued the late flowering phenotype of abi2-2. Interestingly, phosphorylation and protein stability of ABA INSENSITIVE 5 (ABI5) were enhanced in abi2-2 plants suggesting that ABI2 dephosphorylates ABI5, thereby reducing protein stability and the capacity to induce FLC expression. Our findings uncovered the unexpected role of ABI2 in promoting flowering by inhibiting ABI5-mediated FLC expression in Arabidopsis.
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