Evidence map›Paper›PMID 38280110›Full record

ArticleMolecular neurobiology2024

Induction of Phosphorylated Tau Accumulation and Memory Impairment by Bisphenol A and the Protective Effects of Carnosic Acid in In Vitro and In Vivo.

Shaoi Hsu, Huichi Huang, Chunhuei Liao, Hsiyun Huang, Yachen Shih, Jingwei Chen, Hanting Wu, Tzuyu Kuo, Ruhuei Fu, Chiawen Tsai

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Shaoi Hsu *Department of Nutrition, China Medical University, Taichung, Taiwan.
Huichi HuangDepartment of Chinese Pharmaceutical Science and Chinese Medicine Resources, China Medical University, Taichung, Taiwan.
Chunhuei LiaoDepartment of Nutrition, China Medical University, Taichung, Taiwan.
Hsiyun HuangDepartment of Nutrition, China Medical University, Taichung, Taiwan.
Yachen ShihDepartment of Nutrition, China Medical University, Taichung, Taiwan.
Jingwei ChenDepartment of Nutrition, China Medical University, Taichung, Taiwan.
Hanting WuDepartment of Nutrition, China Medical University, Taichung, Taiwan.
Tzuyu KuoDepartment of Nutrition, China Medical University, Taichung, Taiwan.
Ruhuei Fu *Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.
Chiawen TsaiDepartment of Nutrition, China Medical University, Taichung, Taiwan. cwtsai@mail.cmu.edu.tw.ORCID http://orcid.org/0000-0003-0101-5696
China Medical University · TW

Funding

China Medical University CMU111-MF-77China Medical University CMU112-MF-68Ministry of Science and Technology MOST 110-2320-B-039-050-MY3
6 · The paper itself

Abstract

Bisphenol A (BPA) is a component of polycarbonate plastics that has been implicated in memory impairment. The present study investigated the effect of carnosic acid (CA) on memory deficit induced by BPA and the role of Akt in this mechanism. First, SH-SY5Y cells were treated with 20 nM BPA and 1 μM CA for 12 h. The results showed that treatment of CA with BPA improved the alternation of IRS-1/Akt/GSK-3β as well as the induction of ApoE and

Indexed as

AbietanesBenzhydryl CompoundsMemory DisordersMice, Inbred C57BLPhenolstau ProteinsAnimalsBisphenol A CompoundsCell Line, TumorHumansLong-Term PotentiationMaleMaze LearningMiceNeuroprotective AgentsPhosphorylationAbietanesBenzhydryl Compoundsbisphenol ABisphenol A CompoundsNeuroprotective AgentsPhenolsProto-Oncogene Proteins c-aktsalvintau ProteinsBisphenol AC57BL/6 miceCarnosic acidMemorySH-SY5Y cellsSynaptic plasticity

Identifiers

PMID38280110
OpenAlexW4391276975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.