Evidence map›Paper›PMID 38280082›Full record

ArticleVeterinary research communications2024

Effective treatment of sarcoptic mange in an alpaca (Vicugna pacos) using fluralaner: a case report.

Giulia Sala, Alessia Libera Gazzonis, Davide Pravettoni, Alessandra Cafiso, Guido Grilli, Vincenzo Ferrulli, Antonio Boccardo, Federica Di Cesare, Laura Filippone Pavesi, Sergio Zanzani

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Veterinary research communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Giulia SalaDepartment of Veterinary Sciences, University of Pisa, via Livornese s.n.c, San Piero a Grado, 56122, Italy.
Alessia Libera GazzonisDepartment of Veterinary Medicine and Animal Sciences, Università degli Studi di Milano, via dell'Università 6, Lodi, 26900, Italy.
Davide PravettoniDepartment of Veterinary Medicine and Animal Sciences, Università degli Studi di Milano, via dell'Università 6, Lodi, 26900, Italy. davide.pravettoni@unimi.it.
Alessandra CafisoDepartment of Veterinary Medicine and Animal Sciences, Università degli Studi di Milano, via dell'Università 6, Lodi, 26900, Italy.
Guido GrilliDepartment of Veterinary Medicine and Animal Sciences, Università degli Studi di Milano, via dell'Università 6, Lodi, 26900, Italy.
Vincenzo FerrulliDepartment of Veterinary Medicine and Animal Sciences, Università degli Studi di Milano, via dell'Università 6, Lodi, 26900, Italy.
Antonio BoccardoDepartment of Veterinary Medicine and Animal Sciences, Università degli Studi di Milano, via dell'Università 6, Lodi, 26900, Italy.
Federica Di CesareDepartment of Veterinary Medicine and Animal Sciences, Università degli Studi di Milano, via dell'Università 6, Lodi, 26900, Italy.
Laura Filippone PavesiDepartment of Veterinary Medicine and Animal Sciences, Università degli Studi di Milano, via dell'Università 6, Lodi, 26900, Italy.
Sergio ZanzaniDepartment of Veterinary Medicine and Animal Sciences, Università degli Studi di Milano, via dell'Università 6, Lodi, 26900, Italy.
University of Milan · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

South American Camelids, including alpacas, have gained popularity in Europe as pets and prized wool sources. Skin health concerns, particularly mite infestations, have emerged as a notable problem in these animals. Sarcoptic mange can lead to severe itching, papules, and chronic symptoms such as alopecia, crusts, and emaciation if left untreated. This case report documents a 2-year-old female alpaca suffering from sarcoptic mange. Despite initial treatment with ivermectin, its condition worsened, leading to severe weight loss, abortion, and a continued presence of mites. Considering the lack of effective treatments for sarcoptic mange in alpacas and the unavailability of registered drugs for this species in Italy, fluralaner, a drug previously used in other animal species, has been administered orally at a dosage of 5 mg/kg. Within a week after the treatment with fluralaner, the patient exhibited significant improvement, including the resolution of itching, healing of skin lesions, and an increase in appetite. Follow-up skin scrapings confirmed the absence of mites, and the patient's condition continued to improve. Fluralaner demonstrated to be a highly effective and fast-acting treatment for sarcoptic mange in alpacas, offering potential economic benefits attributed to its single-dose administration.

Indexed as

Camelids, New WorldIsoxazolesScabiesAcaricidesAnimalsFemaleA1443 compoundAcaricidesIsoxazolesAlpacaFluralanerSarcoptes scabieiSarcoptic mangeSouth American camelids

Identifiers

PMID38280082
PMCPMC11147896
OpenAlexW4391274916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.