Evidence map›Paper›PMID 38279995›Full record

ArticleCancer immunology, immunotherapy : CII2024

Cytokine-induced killer (CIK) cells, successes and challenges: report on the first international conference dedicated to the clinical translation of this unique adoptive cell immunotherapy.

Amit Sharma, Xiubao Ren, Antonio Rosato, Dario Sangiolo, Zibing Wang, Sarah Tettamanti, Yi Zhang, Eva Rettinger, Kevin Aaron Fenix, Roberta Sommaggio and 2 more

Abstract read
In one paragraph

Article in Cancer immunology, immunotherapy : CII, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Amit SharmaDepartment of Integrated Oncology, Center for Integrated Oncology (CIO) Bonn, University Hospital Bonn, Bonn, Germany.
Xiubao RenTianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, China.
Antonio RosatoDepartment of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy.
Dario SangioloDepartment of Oncology, University of Turin, Turin, Italy.
Zibing WangImmunotherapy Department, Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, China.
Sarah TettamantiTettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
Yi ZhangBiotherapy Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Eva RettingerFrankfurt Cancer Institute (FCI), Goethe University, Frankfurt am Main, Germany.
Kevin Aaron FenixDiscipline of Surgery, Adelaide Medical School, The University of Adelaide, Adelaide, SA, Australia.
Roberta SommaggioDepartment of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy.
Elisa CappuzzelloImmunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.
Ingo G H Schmidt-WolfDepartment of Integrated Oncology, Center for Integrated Oncology (CIO) Bonn, University Hospital Bonn, Bonn, Germany. ingo.schmidt-wolf@ukbonn.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

On August 30, 2023, experts from Germany and abroad met to discuss the successes and challenges of cytokine-induced killer cell (CIK) therapy, that recently celebrated its 30th anniversary providing treatment for cancer. This first virtual conference was hosted by CIO Bonn, a certified Comprehensive Cancer Center (CCC) funded by German Cancer Aid (DKH). In addition to keynote speakers involved in CIK cell clinical trials or optimized preclinical models to improve this adoptive cell immunotherapy, more than 100 attendees from around the world also participated in this event. Initiatives to establish the International Society of CIK Cells (ISCC) and a stronger CIK cell network guiding preclinical research and future clinical trials were also announced.

Indexed as

Cytokine-Induced Killer CellsNeoplasmsCytokinesGermanyHumansImmunotherapyImmunotherapy, AdoptiveCytokinesCancerCytokine-induced killer (CIK) cell therapyImmunotherapies

Identifiers

PMID38279995
PMCPMC10821962

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.