Evidence map›Paper›PMID 38279742›Full record

ReviewRecent patents on biotechnology2025

Edible Vaccines: A Patent-Driven Exploration of Immunization Technologies.

Sahil Kashyap, Rohit Kamboj, Shikha Kamboj, Kumar Guarve, Sweta Kamboj

Abstract readReview
PubMed Publisher
In one paragraph

Review in Recent patents on biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sahil KashyapDepartment of Pharmaceutical Sciences, Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, India.
Rohit KambojDepartment of Pharmaceutical Sciences, Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, India.
Shikha KambojDepartment of Pharmaceutical Sciences, Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, India.
Kumar GuarveDepartment of Pharmaceutical Sciences, Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, India.
Sweta KambojDepartment of Pharmaceutical Sciences, Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, India.
Guru Gobind Singh Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccines are biological preparations that improve immunity to particular diseases. Particularly for poor developing nations, edible vaccines show significant potential as a financially advantageous, simple to administer, straightforward to store, fail-safe, and socially and culturally acceptable vaccine delivery system. A vaccine incorporates the gene-encoding bacterial or viral disease-causing agent in plants without losing its immunogenic property. Potatoes, tomatoes, rice, soybeans, and bananas are the primary plants for edible vaccines. It activates the systemic and mucosal immunity responses against a foreign disease-causing organism. It offers exciting possibilities to reduce diseases like hepatitis B, rabies, HIV/AIDS (human immunodeficiency virus infection and acquired immune deficiency syndrome), etc. These vaccines provide many benefits, like being convenient to administer, efficiently storing, and readily acceptable drug delivery systems for patients of different age groups. So, an edible vaccine may be the most convenient vaccine to improve immunity. However, there are a lot of technical and regulatory challenges to overcome in the way of edible vaccine technology. Though all seem surmountable, various technical obstacles and regulatory and non-scientific challenges need to be overcome. Moreover, edible vaccine patents represent a cutting-edge area of biotechnology, where the integration of genetic material into edible substances holds great promise for revolutionizing vaccination methods. These patents aim to harness the potential of plants and other edibles to stimulate immune responses, offering a potential alternative to traditional injectable vaccines. This review states the technologies, host plants, current status, recent patents, the future of this new preventive modality, and different regulatory issues concerning edible vaccines.

Indexed as

ImmunizationPatents as TopicVaccines, EdibleAnimalsHumansPlants, Genetically ModifiedVaccines, EdiblebiotechnologyEdible vaccineimmunization technologiesmechanism of action of edible vaccinetransgenic plantvaccine delivery.

Identifiers

PMID38279742
OpenAlexW4391253094

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.