Evidence map›Paper›PMID 38279721›Full record

ReviewCurrent drug discovery technologies2024

A Review on Synthetic Thiazole Derivatives as an Antimalarial Agent.

Tutumoni Kalita, Ankita Choudhury, Anshul Shakya, Surajit Kumar Ghosh, Udaya Pratap Singh, Hans Raj Bhat

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current drug discovery technologies, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Investigation of Potent Anti-Drug design, development and therapy · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tutumoni KalitaDepartment of Pharmaceutical Sciences, Girijananda Chowdhury Institute of Pharmaceutical Science, Hatkhowapara, Azara, Guwahati, Assam, India.
Ankita ChoudhuryDepartment of Pharmacy, Silchar Medical College and Hospital, Silchar, Assam, India.
Anshul ShakyaDepartment of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, Assam, 786004, India.
Surajit Kumar GhoshDepartment of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, Assam, 786004, India.
Udaya Pratap SinghDrug Design & Discovery Laboratory, Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology & Sciences, Allahabad, Uttar Pradesh, 211007, India.
Hans Raj BhatDepartment of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, Assam, 786004, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThiazole is a widely studied core structure in heterocyclic chemistry and has proven to be a valuable scaffold in medicinal chemistry. The presence of thiazole in both naturally occurring and synthetic pharmacologically active compounds demonstrates the adaptability of these derivatives.

methodsThe current study attempted to review and compile the contributions of numerous researchers over the last 20 years to the medicinal importance of these scaffolds, with a primary focus on antimalarial activity. The review is based on an extensive search of PubMed, Google Scholar, Elsevier, and other renowned journal sites for a thorough literature survey involving various research and review articles.

resultsA comprehensive review of the antimalarial activity of the thiazole scaffold revealed potential therapeutic targets in

conclusionThis article intends to point researchers in the right direction for developing potential thiazole-based compounds as antimalarial agents in the future.

Indexed as

AntimalarialsThiazolesAnimalsHumansMalariaPlasmodiumStructure-Activity RelationshipAntimalarialsThiazolesantimalarial activityanti-parasitic.biological activityplasmodium falciparumpotential leadThiazole derivatives

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.