Evidence map›Paper›PMID 38279349›Full record

ArticleInternational journal of molecular sciences2024

The Effect of S-Allyl L-Cysteine on Retinal Ischemia: The Contributions of MCP-1 and PKM2 in the Underlying Medicinal Properties.

Windsor Wen-Jin Chao, Howard Wen-Haur Chao, Hung-Fu Lee, Hsiao-Ming Chao

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Retinal Ischemia: Therapeutic Effects and Mechanisms of Paeoniflorin.International journal of molecular sciences · 2025
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Windsor Wen-Jin ChaoDepartment of Medicine, Aston Medical School, Aston University, Birmingham B4 7ET, UK.
Howard Wen-Haur ChaoDepartment of Science, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Hung-Fu LeeDepartment of Neurosurgery, Cheng Hsin General Hospital, Taipei 11220, Taiwan.
Hsiao-Ming ChaoDepartment of Chinese Medicine, School of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.ORCID 0000-0002-1545-9936
University of British Columbia · CANational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinal ischemia plays a vital role in vision-threatening retinal ischemic disorders, such as diabetic retinopathy, age-related macular degeneration, glaucoma, etc. The aim of this study was to investigate the effects of S-allyl L-cysteine (SAC) and its associated therapeutic mechanism. Oxidative stress was induced by administration of 500 μM H

Indexed as

GlaucomaNeuroprotective AgentsReperfusion InjuryRetinal DiseasesAnimalsAnti-Inflammatory AgentsCysteineHydrogen PeroxideIschemiaRatsRats, WistarAnti-Inflammatory AgentsCysteineHydrogen PeroxideNeuroprotective AgentsS-allylcysteinehydrogen peroxidemonocyte chemoattractant protein-1oxidative stresspyruvate kinase M2retinal ganglion cellretinal ischemiaretinal pigment epitheliumS-allyl L-cysteine

Identifiers

PMID38279349
PMCPMC10816972
OpenAlexW4391089660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.