Evidence map›Paper›PMID 38279315›Full record

ReviewInternational journal of molecular sciences2024

Advancements in Allergen Immunotherapy for the Treatment of Atopic Dermatitis.

Bei-Cyuan Guo, Kang-Hsi Wu, Chun-Yu Chen, Wen-Ya Lin, Yu-Jun Chang, Mao-Jen Lin, Han-Ping Wu

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. From Pathways to Patients in Atopic Dermatitis: Advanced Systemic Therapies.International journal of molecular sciences · 2025
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 1 country.

Bei-Cyuan GuoDepartment of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70403, Taiwan.ORCID 0000-0003-1391-6264
Kang-Hsi WuDepartment of Pediatrics, Chung Shan Medical University Hospital, Taichung 40201, Taiwan.ORCID 0000-0001-9145-0522
Chun-Yu ChenDepartment of Emergency Medicine, Tungs' Taichung Metro Harbor Hospital, Taichung 43503, Taiwan.
Wen-Ya LinDepartment of Pediatrics, Taichung Veteran General Hospital, Taichung 43503, Taiwan.
Yu-Jun ChangLaboratory of Epidemiology and Biostastics, Changhua Christian Hospital, Changhua 50006, Taiwan.ORCID 0000-0002-1433-6002
Mao-Jen LinDivision of Cardiology, Department of Medicine, Taichung Tzu Chi Hospital, The Buddhist Tzu Chi Medical Foundation, Taichung 42743, Taiwan.
Han-Ping WuCollege of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0002-0069-4183
Chang Gung University · TWChanghua Christian Hospital · TWChung Shan Medical University Hospital · TWNational Cheng Kung University Hospital · TWTaichung Veterans General Hospital · TWTungs' Taichung MetroHarbor Hospital · TWTzu Chi University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis (AD) is a chronic inflammatory skin condition that affects individuals of all age groups, manifesting as a spectrum of symptoms varying from mild to severe. Allergen immunotherapy (AIT) involves the administration of allergen extracts and has emerged as a potential treatment strategy for modifying immune responses. Its pathogenesis involves epidermal barrier dysfunction, microbiome imbalance, immune dysregulation, and environmental factors. Existing treatment strategies encompass topical steroids to systemic agents, while AIT is under investigation as a potential immune-modifying alternative. Several studies have shown reductions in the severity scoring of atopic dermatitis (SCORAD) scores, daily rescue medication use, and visual analog scale (VAS) scores following AIT. Biomarker changes include increased IgG4 levels and decreased eosinophil counts. This review provides valuable insights for future research and clinical practice, exploring AIT as a viable option for the management of AD.

Indexed as

Dermatitis, AtopicDesensitization, ImmunologicEpidermisHumansImmunoglobulin GSteroidsImmunoglobulin GSteroidsallergen immunotherapyatopic dermatitiseczematreatment

Identifiers

PMID38279315
PMCPMC10816003
OpenAlexW4391105310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.